Results 81 to 90 of about 1,286,583 (307)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Security as an Object of Public Administration

open access: yesУправленческие науки, 2018
Subject. Security is an essential element of the public (public) sector of the economy, the maintenance of which accounts for a significant amount of budgetary resources.
O. M. Roy
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

A DANGEROUS TENDENCY IN PUBLIC HEALTH ADMINISTRATION [PDF]

open access: yesAmerican Journal of Public Health, 1919
The “dangerous tendency” is that towards a division in Federal and state health administration. Its remedy lies in planning and developing a strong, alert Federal health agency properly related in its activities to the public health interests of the States.
openaire   +2 more sources

Book Review: Our Schools are at Risk [PDF]

open access: yes, 2014
Book review of: Diane Ravitch, Reign of Error: The Hoax of the Privatization Movement and the Danger to American Public Schools (New York: Knopf, 2013)
Bodi, John Michael
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

On The Issue of the Categorization of Administrative Offences

open access: yesСибирское юридическое обозрение, 2020
Some problems of modern administrative-tort and criminal legislation and law are considered. On the positive side, the sequence of the legislator is assessed regarding the delimitation of the norms of criminal and administrative responsibility. Attention
V. I. Surgutskov
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

University proceedings. Volga region. Social sciences

open access: yesИзвестия высших учебных заведений. Поволжский регион: Общественные науки
Background. The crime provided for in Article 148 of the Criminal Code of the Russian Federation causes problems in qualification due to the ambiguity of the object ofthis criminal encroachment.
I.А. Efremova
doaj   +1 more source

The Pestilence of London: Women, Hygiene, Prostitution and Pollution [PDF]

open access: yes, 2012
Depictions of women and water during the Great Stink of London were bound up with moral and medical fears of the mid to late nineteenth century. Specifically, I will look at a paint by each of the following artists: Sir John Everett Millais, John Rodham ...
Freestone, Sophie
core   +1 more source

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