Results 51 to 60 of about 2,395,147 (354)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
« Déguerpir » pour reconquérir l’espace public à Abidjan.
L'Espace Politique, 2014 For several decades, evictions have been used in the Ivory Coast as a way to regulate the urban domain. In order to better control urban development, governmental and municipal authorities have used this method to curb the illegal occupation of public ...
Christian Bouquet, Irène Kassi-Djodjo
doaj +1 more source
Biodiversity conservation and intellectual property law: A conceptual misunderstanding [PDF]
Anali Pravnog Fakulteta u Beogradu, 2017 The author has set up a thesis on conceptual incompatibility of intellectual property rights and the objectives of the Convention on the protection of biodiversity.
Marković Slobodan
doaj +1 more source
The internet and public–private governance in the European Union [PDF]
, 2006 The EU plays a significant role in public policy aspects of Internet governance, having created in the late 1990s the dot eu Internet Top Level Domain (TLD). This enables users to register names under a European online address label.
Christou, George, Simpson, Seamus
core +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Collaborating in the Public’s Domain
CeROArt : Conservation, Exposition, Restauration d'Objets d'Art, 2009 Since the 1980s conservators have found innovative ways to use the Internet to collaboratively create and share information around cultural property. The rise of “Web 2.0,” the advent of social media applications, and other technological advancements ...
Richard McCoy
doaj +1 more source
The Limitations and Possibilities of Co-Creation in the Public Domain of Rotterdam [PDF]
, 2012 A group of undergraduate bachelor students engaged in a project that focused on finding new co-creation methods for the public domain in Rotterdam. This paper describes the context in which the students worked, the findings they\ud made and the solutions
Nordeman, Levien, Visser, Eva
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Eminent Domain after Kelo v. City of New London: Compensating for the Supreme Court’s Refusal to Enforce the Fifth Amendment [PDF]
, 2007 Governments, both state and federal, have the right to take private property for public use, provided that just compensation is paid. The Fifth Amendment to the United States Constitution sets the legal standard for these propositions; this power is ...
Mikkelsen, Scott D.
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source