Results 61 to 70 of about 2,686,418 (304)

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

L’évolution du droit minier chilien (1874-1971)

open access: yesLes Cahiers ALHIM, 2014
From 1811 to 1976, four mining codes succeeded each other in Chile. This legal instability shows difficult it was for the legislator to abandon the colonial legal system and to adjust to the mining reality of the country.
Zunilda Carvajal-DelMar
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Reclaiming the Promise of the Judicial Branch: Toward a More Meaningful Standard of Judicial Review as Applied to New York Eminent Domain Law [PDF]

open access: yes, 2011
This Article asserts that the New York model of eminent domain and judicial review must be reworked to provide a meaningful balance between private property rights and concerns for public good.
Franzese, Paula
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

著作權法最新發展趨勢 Current Developments of Copyright [PDF]

open access: yesKējì Fǎxué Pínglùn, 2005
現代科技之發展日新月異,對於智慧財產權保護之關切日益增加,尤其是著作權法領域更因網際網路之衝擊而備受矚目,有論者形容著作權發展史等同於科技發展史,足見著作權法制與科技發展關係之密切,其中著作權人與公共領域間利益之衝突自始以來均為著作權法之重心,如何調和此二者並使現行法律規範合於數位時代之需求乃首要之務。 本文回顧 2003 年至2004 年間著作權法之發展趨勢,除介紹美國、歐盟及我國著作權法制最新立法方向之外,並針對著作權保護期間之延長、實質相似性之判斷、P2P 之紛爭、補償金制度、DMCA 之爭議 ...
蔡惠如 Huei-ju Tsai
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

EXCLUSION OF STATE CLAIMS FROM THE SCOPE OF STATUTE OF LIMITATIONS RULES [PDF]

open access: yesLegal Bulletin
The relevance of the study is determined by the adoption of the Constitutional Court of the Russian Federation Resolution No. 49-P of October 31, 2024, which established that No.
KIRPICHEV A.E.
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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