Results 61 to 70 of about 14,096,515 (294)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
著作權法最新發展趨勢 Current Developments of Copyright [PDF]
Kējì Fǎxué Pínglùn, 2005 現代科技之發展日新月異，對於智慧財產權保護之關切日益增加，尤其是著作權法領域更因網際網路之衝擊而備受矚目，有論者形容著作權發展史等同於科技發展史，足見著作權法制與科技發展關係之密切，其中著作權人與公共領域間利益之衝突自始以來均為著作權法之重心，如何調和此二者並使現行法律規範合於數位時代之需求乃首要之務。 本文回顧 2003 年至2004 年間著作權法之發展趨勢，除介紹美國、歐盟及我國著作權法制最新立法方向之外，並針對著作權保護期間之延長、實質相似性之判斷、P2P 之紛爭、補償金制度、DMCA 之爭議 ...
蔡惠如 Huei-ju Tsai
doaj
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Revista de Biología Tropical, 2009 La Constitución Política de Costa Rica incluye un párrafo sobre el derecho a un ambiente sano, la responsabilidad del Estado a garantizar, defender y preservar ese derecho, así como la acción popular (Artículo 50).
Gabriel Quesada A
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The Importance of Classifying an Asset as Belonging to the Public Domain
Bulletin of the Transilvania University of Braşov: Series VII: Social Sciences, LawAccording to the special Law no. 165/2013 regarding the measures to complete the restitution process, the Local Land Fund Commissions drew up the validation proposal from Annex no.
Catalina-Georgeta Dinu
doaj +1 more source
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
EXCLUSION OF STATE CLAIMS FROM THE SCOPE OF STATUTE OF LIMITATIONS RULES [PDF]
Legal BulletinThe relevance of the study is determined by the adoption of the Constitutional Court of the Russian Federation Resolution No. 49-P of October 31, 2024, which established that No.
KIRPICHEV A.E.
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, 2015 Common Culture exhibited a series of photo-posters from their Binge series. Public Domain, in Platform in Project @ Art-Athina Stand 25 4-7 June 2015, Faliron Pavilion, Athens, Greece.
Campbell, David +3 more
core
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source