Results 51 to 60 of about 2,686,418 (304)
Novelty Determination Using the Inherency Doctrine
Journal of Intellectual PropertySupreme Court decision 2017Hu1304 has established an inherency doctrine in determining novelty. According to the decision, it is not enough to simply show the possibility or probability that something can be done to show prior art to be the same as the ...
Insu Yang
doaj +1 more source
Water governance and institutional change [PDF]
, 2004 This dissertation is about water governance and institutional change. The focus on water governance means that we are interested in collective action with respect to water issues, which is not restricted to government action by public authorities, but ...
Kuks, S.M.M.
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Biodiversity conservation and intellectual property law: A conceptual misunderstanding [PDF]
Anali Pravnog Fakulteta u Beogradu, 2017 The author has set up a thesis on conceptual incompatibility of intellectual property rights and the objectives of the Convention on the protection of biodiversity.
Marković Slobodan
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
TRANSFER OF PROPERTY ASSETS [PDF]
Challenges of the Knowledge Society, 2018 Starting from the current jurisprudence on the transfer of property assets, in this article, using logical interpretation and also comparative analysis, we intend to investigate the conditions under which an asset from the private domain of the state ...
Vasilica NEGRUŢ
doaj
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
International Journal of the Commons, 2009 The past three decades have witnessed a period of great turbulence in the economies of biological knowledge, during which there has been great uncertainty as to how and where boundaries could be drawn between public or private knowledge especially with ...
Mark Harvey, Andrew McMeekin
doaj +1 more source
An Efficient Analytical Solution to Thwart DDoS Attacks in Public Domain
, 2009 In this paper, an analytical model for DDoS attacks detection is proposed, in which propagation of abrupt traffic changes inside public domain is monitored to detect a wide range of DDoS attacks.
Gupta, B. B., Joshi, R. C., Misra, Manoj
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Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source