Results 111 to 120 of about 1,694,874 (307)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Institution Formation in Public Goods Games [PDF]
Centralized sanctioning institutions are of utmost importance for overcoming free-riding tendencies and enforcing outcomes that maximize group welfare in social dilemma situations. However, little is known about how such institutions come into existence.
Kosfeld, Michael +2 more
core +4 more sources
Is There an Equity-Efficiency Trade-Off in School Finance? Tiebout and a Theory of the Local Public Goods Producer [PDF]
New empirical work shows the degree of competition among public providers of local public goods or between public and private providers of local public goods matters. This evidence needs a theory of the local public goods producer.
Caroline M. Hoxby
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Good publication practice [PDF]
Acta Obstetricia et Gynecologica Scandinavica, 1994 openaire +2 more sources
Subscription equilibria with public production: Existence and regularity [PDF]
We revisit the analysis of subscription equilibria in a full fledged general equilibrium model with public goods. We study the case of a nonprofit, or public, firm that produces the public good using private goods as inputs, which are to be financed by ...
Villanacci, Antonio, Zenginobuz, Unal
core +1 more source
THE PECULIARITIES OF BUDGETARY FINANCING THE PUBLIC GOODS PRODUCTION IN THE EUROPEAN UNION COUNTRIES: THE LESSONS OF POLAND FOR UKRAINE [PDF]
, 2014 The peculiarities of distribution and use of budgetary facilities for the public goods production in the EU countries, including Poland, are considered and possibilities of adaptation of this experience to the Ukrainian conditions are determined in the ...
Kichurchak, Marianna
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
, 2019 Supplying public goods generates costs and benefits that can be allocated among individuals in different ways. Yet leading theories of justice within liberalism fail to offer concrete guidance on how these allocations should be assessed. This chapter critically examines a number of principles of distributive justice that might be used for this purpose.
Miller, D, Taylor, I
openaire +1 more source
Household Size Economies: Malaysian Evidence [PDF]
People live in households with different size and composition and they consume a variety of goods; categorised as private and public goods. With the existence of public goods in the household, doubling the household size need not increase the consumption
Gillis Maclean +2 more
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