Results 121 to 130 of about 1,694,874 (307)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

EVALUATION OF PUBLIC GOODS -THE COUNTERPOINTS AND CONTRADICTIONS OF THE CROATIAN CONCEPT OF ‘GOODS OF INTEREST TO THE REPUBLIC OF CROATIA’

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2009
In this paper the author analyses the dominant concept about ‘public things’ and in particular the question of the nature of public property. Also analysed are the viewpoints which see goods in public property as some kind of private property.
Branko Babac
doaj  

The Political Economy of Publicly Provided Private Goods [PDF]

open access: yes
A large share of public funds is spent on private goods (education, health care, day care, etc.). This paper integrates two different approaches to the analysis of public provision of private goods.
Blomquist, Sören, Christiansen, Vidar
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Understanding the Challenges of the Digital Economy: The Nature of Digital Goods [PDF]

open access: yes
This article investigates the economic nature and characteristics of digital goods. Such goods are, due to their replicability, shown to be public goods (albeit in an evolutionary way) and durable goods.
Thierry RAYNA
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

CONTRUCTING A BROADER MEASURE OF WELFARE INCORPORATING THE ACCESS TO PUBLIC GOODS [PDF]

open access: yes
This paper attempts to construct a broader measure of welfare that takes in account the access people have to some public goods. If the data on household access to public goods and private assets is assumed to be the result of a maximization problem, a ...
Felipe Diniz
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

INDIVIDUAL usE of general – usE goods in Croatia: Ranges and limitations

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2009
General- use goods are common goods in general usage. The use of general- use goods can be communal and individual. Communal use of general -use goods is anonymous and impersonal, free and equitable.
Damir Aviani
doaj  

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