Results 111 to 120 of about 5,437,298 (346)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

The Warren Court and the Concept of a Right [PDF]

open access: yes, 1999
The Warren Court is dead. None of its Justices remain on the benchindeed, only Justice White survives-and the recent history of the Supreme Court has been in large part a history of repudiating controversial Warren Court doctrines.
Luban, David
core   +1 more source

Creating an International Federation for Public History [PDF]

open access: yes, 2020
This spring, historians from the U.S., Canada, and several other countries will gather in Pensacola, Florida, to create a governing structure for the new International Federation for Public History (IFPH). Why Florida?

core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Origins of the Human Genome Project [PDF]

open access: yes, 1994
Dr. Cook-Deegan recounts some of the scientific and political history leading to controversy about the proper mix of private and public roles in pursuing genome research and bringing its fruits to bear, e.g., in preventing and curing ...
Cook-Deegan, Robert Mullan
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Past Visions of Artificial Futures: One Hundred and Fifty Years under the Spectre of Evolving Machines

open access: yes, 2018
The influence of Artificial Intelligence (AI) and Artificial Life (ALife) technologies upon society, and their potential to fundamentally shape the future evolution of humankind, are topics very much at the forefront of current scientific, governmental ...
Dorin, Alan, Taylor, Tim
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Nationalism, Italy and the Exhibition of the Holocaust: Findings of a Study on the Recently built Museums of Campagna and San Donato

open access: yesEastern European Holocaust Studies
In recent years, Italy has seen a proliferation of Holocaust Museums and Memorials. This article focuses on two recent additions: the Museum of the Twentieth Century and the Shoah in San Donato Val di Comino (Frosinone), and the Memory and Peace Museum ...
Posocco Lorenzo   +2 more
doaj   +1 more source

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