Results 21 to 30 of about 939,121 (301)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Social Intelligence of Librarians and its Role in the increase of the Social Responsibility of Libraries: A Case Study of Public Libraries of Markazi Province [PDF]

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2019
Purpose: The present research aims to explore the role of librarians' social intelligence in increasing the social responsibility of public libraries of Markazi province. Methodology: This is an applied and survey-descriptive research.
Akbar Bahmani, Seyed Mehrdad Seyedin
doaj  

Report on Polish Public Libraries 2001 [PDF]

open access: yes, 2001
Report is an overview of polish public libraries, services to a variety of communities, it also provides statistics, n explanation of the funding policy for public libraries in Poland and information about the governance of public libraries in the ...
Bednarek-Michalska, Bożena   +1 more
core  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

The Effect of Self-efficiency and Psychological Hardiness on Job Burnout through the Mediating Role of Job Motivation (Study Case: the Employees of Public Libraries of Khuzestan Province) [PDF]

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2018
Purpose: The aim of this study is to investigate the effect of self-efficiency and psychological hardiness on job burnout through the mediating role of job motivation among the employees of public libraries of Khuzestan province.
Abbas Hosseinzadeh Bandaghiri   +2 more
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The school-housed public library [PDF]

open access: yes, 1990
Discusses the issue of school-housed public library. Some basic considerations in public libraries; Role and function of public libraries; Importance of advance planning for joint operations of public libraries; Importance of the location of the public ...
Haycock, Ken
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Performance Evaluation of Iran’s Province of Golestan Public Libraries, by Balanced Score Card [PDF]

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2016
Purpose: This study aimed to evaluate the performance of public libraries in Golestan province (Iran) by using Balanced Scorecard (BSC) -a relatively new and multidimensional model to evaluate the holistic performance of organizations- in 2013 ...
maryam babaie-chamazkoti   +1 more
doaj  

Public libraries and political participation, 1870-1940 [PDF]

open access: yes, 2016
The public library movement of the late 19th and early 20th centuries fostered a rapid increase in the number and quality of public libraries in cities and towns across the United States.
Kevane, Michael J, Sundstrom, William A.
core   +1 more source

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