Results 21 to 30 of about 170,282 (312)

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Social Intelligence of Librarians and its Role in the increase of the Social Responsibility of Libraries: A Case Study of Public Libraries of Markazi Province [PDF]

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2019
Purpose: The present research aims to explore the role of librarians' social intelligence in increasing the social responsibility of public libraries of Markazi province. Methodology: This is an applied and survey-descriptive research.
Akbar Bahmani, Seyed Mehrdad Seyedin
doaj  

AFLI Indicators for Measuring Library Performance: An Analytical Developmental Study

open access: yesCybrarians Journal, 2018
The objective of this study is to provide improvement opportunities for the Arab Federation of Libraries and Information (AFLI) indicators to measure library performance.
Emad Abu Eid
doaj   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Performance Evaluation of Iran’s Province of Golestan Public Libraries, by Balanced Score Card [PDF]

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2016
Purpose: This study aimed to evaluate the performance of public libraries in Golestan province (Iran) by using Balanced Scorecard (BSC) -a relatively new and multidimensional model to evaluate the holistic performance of organizations- in 2013 ...
maryam babaie-chamazkoti   +1 more
doaj  

Public Libraries Platform

open access: yesTürk Kütüphaneciliği, 2015
In the article, the Public Libraries Platform, which is formated by a group of public librarians, is introduced for the purpose of taking an initiative to discuss the problems of public libraries and seek solutions.
Ahmet Uğur Özçelik   +3 more
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

The Effect of Self-efficiency and Psychological Hardiness on Job Burnout through the Mediating Role of Job Motivation (Study Case: the Employees of Public Libraries of Khuzestan Province) [PDF]

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2018
Purpose: The aim of this study is to investigate the effect of self-efficiency and psychological hardiness on job burnout through the mediating role of job motivation among the employees of public libraries of Khuzestan province.
Abbas Hosseinzadeh Bandaghiri   +2 more
doaj  

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