Results 61 to 70 of about 3,391,421 (303)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Public poll for support 100 % smoke free area regulation to protect children from secondhand smoke exposure in big city on 8 provinces in Indonesia

Tobacco Induced Diseases, 2018
Objective Support Goverment and parliament to enact a national regulation about 100 % smoke free area for protect children from smoke exposure on all place. Methods 1. The study design was cross-sectional with data collection conducted during the months
Tri Ningsih
doaj   +1 more source

Graphic design in public places under digital transformation

Frontiers in Humanities and Social Sciences
Today, in the digital transformation, graphic design in public places is facing a series of challenges and problems, and the issue of readability of graphic design has gradually become important. Graphic design in public places needs to take into account the needs of all users, including the elderly and special groups, to ensure that the graphic design
openaire   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

How Do Public Perceptions Affect the Security of Connected Places? A Systematic Literature Review

Information
This systematic literature review explores the scholarly debate around public perceptions and behaviors in the context of cybersecurity in connected places. It reveals that, while many articles highlight the importance of public perceptions and behaviors
Agnieszka Dutkowska-Zuk, Joe Bourne, Chengyuan An, Xuan Gao, Oktay Cetinkaya, Peter Novitzky, Gideon Ogunniye, Rachel Cooper, David De Roure, Julie McCann, Jeremy Watson, Tim Watson, Eleri Jones   +12 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Policy entrepreneurship in collaborative governance: transformative innovation in Catalonia’s sustainability transition

Policy Design and Practice
There is increasing recognition that public sectors in Western countries alone cannot tackle complex societal challenges. However, detailed research on the role of public agents in implementing collaborative approaches remains limited.
Míriam Acebillo-Baqué, Diana Velasco, Alejandra Boni   +2 more
doaj   +1 more source

Years of life lost and mortality due to heat and cold in the three largest English cities

Environment International, 2020
There is a well-established relationship between temperature and mortality, with older individuals being most at risk in high-income settings. This raises the question of the degree to which lives are being shortened by exposure to heat or cold. Years of
Katherine Arbuthnott, Shakoor Hajat, Clare Heaviside, Sotiris Vardoulakis   +3 more
doaj   +1 more source

Recruiting hard-to-reach populations to physical activity studies : evidence and experiences [PDF]

, 2010
Most researchers who are conducting research with a public health focus face difficulties in recruiting the segments of the population that they really want to reach.
Baker, Graham, Burton, N. W., Estabrooks, P, Foster, C., Mutrie, Nanette   +4 more
core  

Blood Sugar, Your Pancreas, and Unicorns: The Development of Health Education Materials for Youth With Prediabetes [PDF]

, 2018
Background. The obesity epidemic has led to an increase in prediabetes in youth, causing a serious public health concern. Education on diabetes risk and initiation of lifestyle change are the primary treatment modalities.
Haberlin, Kathryn, Hannon, Tamara S., Lynch, Dustin, Moore, Courtney, Pike, Julie, Taylor, Jennifer, Yazel-Smith, Lisa G.   +6 more
core   +1 more source