Results 111 to 120 of about 2,130,927 (298)
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
M74 public archaeology programme evaluation report [PDF]
Report on public engagement activities with the M74 Public Archaeology Project, a partnership project between Transport Scotland, Glasgow City Council, South Lanarkshire Council and Renfrewshire Council in connection with the M74 Motorway Completion ...
Morton, Diana, Walker, David
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Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source
BASIC CHARACTERISTICS OF PUBLIC PASSENGER TRANSPORT FROM THE TRANSPORT USER POINT OF VIEW
This article deals with problems of public passenger transport from the transport user point of view. Than there are characterized properties of each mode of transport including of course also public passenger transport. Specifically there are following
Rudolf Kampf, Nina Kudláčková
doaj
Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study
ABSTRACT Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited. Those who agreed were followed up for at least 24 weeks.
Peiyu Wang +7 more
wiley +1 more source
The significance of internal integration of public transport for improving offer [PDF]
The article summarises some of the findings of the research Development possibilities for development of public transport and settlement in the Republic of Slovenia, which is one of the first attempts at comprehensive dealing with public transport in the
Aljaž Plevnik, Marjan Lep
doaj
Optimal urban transport pricing with congestion and economies of density [PDF]
The paper analyses the impact of economies of density on the characteristics of an urban transport system under optimal pricing conditions. Optimal pricing rules are derived for a transport system where bus and car modes are available for peak and ...
Kurt Van Dender, Stef Proost
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