Results 211 to 220 of about 6,232,974 (300)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Long-Noncoding RNA PCAT6 Aggravates Osteosarcoma Tumourigenesis via the MiR-143-3p/ZEB1 Axis [Retraction]. [PDF]

Onco Targets Ther
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Bibliometric analysis of slope-correcting osteotomy in the context of anterior cruciate ligament reconstruction: key trends, contributors and themes. [PDF]

Eur J Orthop Surg Traumatol
Loharuka A, Zilani N, Raj S, Babbar D, Mohammad HR, Razak H, Ollivier M.   +6 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Global research trends and emerging themes of ketamine in perioperative neurocognitive disorders: a bibliometric analysis. [PDF]

Front Med (Lausanne)
Kang J, Wang Z, Bi J, Duo Y, Yan W.
europepmc   +1 more source

Small-Molecule Mimetic and Inhibitor-101 Enhances the Antitumor Efficacy of Cisplatin Through Inhibition of Repair and Redox Activity in Non-Small-Cell Lung Cancer [Retraction]. [PDF]

Drug Des Devel Ther
europepmc   +1 more source

Retraction: A Systematic Review and Meta-Analysis of Clinical Effectiveness of Intravenous Magnesium Sulphate in the Treatment of Acute Fast Atrial Fibrillation in Non-surgical Adult Patients. [PDF]

Cureus
Mupunga K, Chandavengerwa W, Nyabadza DP, Masungo AB.   +3 more
europepmc   +1 more source