Results 91 to 100 of about 9,070,746 (256)
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Design and analysis of an efficient distributed event notification service [PDF]
, 2004 Event Notification Services (ENS) use the publish/subscribe paradigm to continuously inform subscribers about events they are interested in. Subscribers define their interest in so-called profiles.
Bittner, Sven, Hinze, Annika
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Beyond TEI: Returning the Text to the Reader
Journal of the Text Encoding Initiative, 2013 Much research and effort has been invested in creating a versatile format for digital texts and the TEI is now widely used in many communities. Much less consolidated thought has been spend to publish and distribute digital texts in ways that are most ...
Christian Wittern
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
, 2006 Sistemas publish-subscribe são definidos por seu modelo básico de comunicação. No entanto, a maior parte dos sistemas publish-subscribe existentes incorpora outros mecanismos em sua implementação. Este trabalho busca um melhor entendimento de sistemas
MARIO MENDES DE O ZIMMERMANN
core +1 more source
Load Balancing Content-Based Publish/Subscribe Systems [PDF]
, 2010 Distributed content-based publish/subscribe systems suffer from performance degradation and poor scalability caused by uneven load distributions typical in real-world applications.
Alex King Yeung Cheung +1 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Modeling publish/subscribe communication systems: Towards a formal approach
, 2003 Publish/subscribe is a widespread communication paradigm for asynchronous messaging that naturally fits the decoupled nature of distributed systems, allowing simple and effective development of distributed applications.
BALDONI, Roberto +3 more
core +1 more source