Results 81 to 90 of about 9,070,746 (256)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Enabling Internet-Scale Publish/Subscribe In Overlay Networks [PDF]

open access: yes, 2011
As the amount of data in todays Internet is growing larger, users are exposed to too much information, which becomes increasingly more difficult to comprehend.
Rahimian, Fatemeh
core  

Performance Testing of Semantic Publish/Subscribe Systems

open access: yes, 2010
Publish/subscribe mechanisms support clients in observing knowledge represented in semantic repositories and responding to knowledge changes. Currently available implementations of semantic publish/subscribe systems differ significantly with respect ...
Stefan Biffl   +9 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

A petri net formalization of a publish-subscribe process system. [PDF]

open access: yes
Publish/subscribe systems are getting more and more integrated into the execution of business processes in process aware information systems. This integration enables the distribution of the process logic and increases the scalability and adaptability of
Hens, Pieter   +3 more
core  

Vitis: A Gossip-based Hybrid Overlay for Internet-scale Publish/Subscribe [PDF]

open access: yes, 2011
Peer-to-peer overlay networks are attractive solutions for building Internet-scale publish/subscribe systems. However, scalability comes with a cost: a message published on a certain topic often needs to traverse a large number of uninterested ...
Payberah, Amir H.   +4 more
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Event-Based and Publish/Subscribe Communication

open access: yes, 2008
Ubiquitous Computing assumes that users and their computing devices are highly mobile. Because it is unlikely that mobile networks will be equally available in the same quality everywhere, there may be varying levels of connectivity, ranging from full ...
Aitenbichler, Erwin, Erwin Aitenbichler
core   +1 more source

Benchmarking Publish/Subscribe-Based Messaging Systems [PDF]

open access: yes, 2010
Publish/subscribe-based messaging systems are used increasingly often as a communication mechanism in data-oriented web applications. Such applications often pose serious performance and scalability challenges.
Samuel Kounev   +7 more
core   +1 more source

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