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External evaluation of published population pharmacokinetic models of posaconazole
Frontiers in Pharmacology, 2022 Population pharmacokinetic (PopPK) models of posaconazole have been established to promote the precision dosing. However, the performance of these models extrapolated to other centers has not been evaluated.
Shuqi Huang +9 more
doaj +4 more sources
SYSTEMATIC EXTERNAL EVALUATION OF PUBLISHED POPULATION PHARMACOKINETIC MODELS FOR TACROLIMUS IN ADULT LIVER TRANSPLANT RECIPIENTS [PDF]
Transplantation, 2020 Background:Diverse tacrolimus population pharmacokinetic models in adult liver transplant recipients have been established to describe the PK characteristics of tacrolimus in the last two decades. However, their extrapolated predictive performance remains unclear.Therefore,in this study,we aimed to evaluate their external predictability and identify ...
Xiaojun Cai +10 more
openaire +6 more sources
The external validity of published randomized controlled trials in primary care [PDF]
BMC Family Practice, 2009 Background A criticism of Randomized Controlled Trials (RCTs) in primary care is that they lack external validity, participants being unrepresentative of the wider population.
Montgomery Alan A +4 more
doaj +4 more sources
External evaluation of published population pharmacokinetic models of tacrolimus in adult renal transplant recipients [PDF]
British Journal of Clinical Pharmacology, 2016 AimSeveral tacrolimus population pharmacokinetic models in adult renal transplant recipients have been established to facilitate dose individualization. However, their applicability when extrapolated to other clinical centres is not clear. This study aimed to (1) evaluate model external predictability and (2) analyze potential influencing factors ...
Chen-Yan, Zhao +3 more
openaire +3 more sources
Internal and External Evaluation of the Book Principles and Methodology of Translation Published by SAMT [PDF]
پژوهشنامۀ انتقادی متون و برنامههای علوم انسانی, 2021 The present research aimed at analyzing the book Principles and Methodology of Translation in terms of its formal characteristics, content, and methodology, using the critical library research method in general and McDonough, Shaw, and Masuhara’s (2013 ...
Alireza Rasti
doaj +2 more sources
Journal of Global Antimicrobial Resistance, 2023 : Objectives: Several linezolid population pharmacokinetic (popPK) models have been established to facilitate optimal therapy; however, their extrapolated predictive performance to other clinical sites is unknown. This study aimed to externally evaluate
Yan Qin +7 more
doaj +3 more sources
Internal, external, and ecological validity in research design, conduct, and evaluation
Indian Journal of Psychological Medicine, 2018 Reliability and validity describe desirable psychometric characteristics of research instruments. The concept of validity is also applied to research studies and their findings.
Chittaranjan Andrade
doaj +2 more sources
Scientific Reports, 2022 Radiomics analyses commonly apply imaging features of different complexity for the prediction of the endpoint of interest. However, the prognostic value of each feature class is generally unclear.
Iram Shahzadi +14 more
semanticscholar +1 more source
External Validation of Deep Learning Algorithms for Radiologic Diagnosis: A Systematic Review.
Radiology: Artificial Intelligence, 2022 Purpose To assess generalizability of published deep learning (DL) algorithms for radiologic diagnosis. Materials and Methods In this systematic review, the PubMed database was searched for peer-reviewed studies of DL algorithms for image-based ...
Alice C Yu, Bahram Mohajer, J. Eng
semanticscholar +1 more source
Investigation and analysis on the current status of single-arm clinical trial with external control [PDF]
Yixue xinzhi zazhi, 2022 Objective To study the progress of single-arm trials with external controls using bib-liometric methods and compare Chinese and foreign literature to understand research directions and trends.Methods We performed computer searches of five databases ...
Jia-Ning LIU +5 more
doaj +1 more source