Results 71 to 80 of about 6,268,392 (295)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Comments on "Publisher’s Note" on papers on individual external dose monitoring of all citizens of Date City

open access: yes, 2021
We point out that the recently published Publisher’s Note concerning two retractions in Journal of Radiological Protection and the retraction notices contain various incorrect statements, misrepresentations of facts and omission of important events.
Yoh Tanimoto   +5 more
openaire   +3 more sources

External validation of a Cox prognostic model: principles and methods

open access: yesBMC Medical Research Methodology, 2013
BackgroundA prognostic model should not enter clinical practice unless it has been demonstrated that it performs a useful role. External validation denotes evaluation of model performance in a sample independent of that used to develop the model.
P. Royston, D. Altman
semanticscholar   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Prediction Models and Their External Validation Studies for Mortality of Patients with Acute Kidney Injury: A Systematic Review.

open access: yesPLoS ONE, 2017
ObjectivesTo systematically review AKI outcome prediction models and their external validation studies, to describe the discrepancy of reported accuracy between the results of internal and external validations, and to identify variables frequently ...
Tetsu Ohnuma, Shigehiko Uchino
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Publishing and Society: A Comparative Analysis of Bourdieu's Field Theory and Paradigm of External Analysis using the Case of the Book Publishing Industry in China

open access: yesBCP Social Sciences & Humanities, 2021
The publishing industry has a long history of development as an integral part of people's social life. This essay provides a preliminary exploration of the special status of the publishing industry in sociological research through a comparative analysis of Bourdieu's field theory and the Marxist-oriented external analysis paradigm.
openaire   +2 more sources

Prediction models for the risk of spontaneous preterm birth based on maternal characteristics: a systematic review and independent external validation

open access: yesActa Obstetricia et Gynecologica Scandinavica, 2018
Prediction models may contribute to personalized risk‐based management of women at high risk of spontaneous preterm delivery. Although prediction models are published frequently, often with promising results, external validation generally is lacking.
L. Meertens   +9 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The influence of external economic policy fluctuation on enterprise productivity: Based on Chinese listed enterprises

open access: yesTechnological and Economic Development of Economy
Drawing upon a comprehensive dataset encompassing Chinese publicly traded enterprises across the two-decade span from 2000 to 2020, this article analyzes the effects of external economic policy variations on the productivity of Chinese enterprises.
Songbo Jia   +4 more
doaj   +1 more source

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