Results 121 to 130 of about 6,584,582 (379)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Stronger Together: Library-led Open Access Publishing in Scotland

open access: yes027.7
The purpose of this article is to look at library-led Open Access publishing initiatives across Scotland: particularly the Scottish Confederation of University and Research Libraries (SCURL) Open Hosting Shared Service and Scottish Universities Press ...
Dominique Walker, Rebecca Wojturska
doaj   +1 more source

Production of Arabic Fonts for use in Printing Equipment

open access: yesJournal of Architecture, Art & Humanistic Science, 2018
The printing process is increasing and spreading as a result of the emergence of modern trends in the field of printing and publishing. The trend towards the use of computers in digital printing systems has increased, which increases the degree of ...
Sameh Hassan   +2 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

A publishing modality to advance social justice: an African experience

open access: yes027.7
There are many Africans who hold the view that the philanthropic underpinnings of the openness movement have been hijacked by commercial publishers, violating the altruistic principles of open access to advance a business model that guarantees exorbitant
Reggie Raju, Kaela de Lillie
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Pollution, hazards, and health inequalities: a longitudinal exploration of the impact of PM2.5 on depression among rural older adults with different incomes in China

open access: yesHumanities & Social Sciences Communications
Air pollution has been increasingly associated with heightened mental health risks. However, there is a scarcity of nationwide research addressing the mental health issue of rural older adults, as well as a lack of thorough investigations into the ...
Zhenhua Zheng   +4 more
doaj   +1 more source

Design of Websites intended for Arabic child and the extent of the impact of different civilizations

open access: yesJournal of Architecture, Art & Humanistic Science, 2017
Websites are an important element to get information at the present time .and It was no surprise on us and we are in the digital information society to find that the most important visitors to the internet At the age of only a few years, children today ...
Neveen Salah   +2 more
doaj   +1 more source

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