Results 91 to 100 of about 6,488 (202)

Optimization on extraction technology of puerarin from Puerarialobata

, 2016
In order to explore the optimum conditions of puerarin, the extraction process was optimized by single factor test and response surface design. The extract was identified by high performance liquid chromatography (HLPC) for puerarin or not.The results ...
Qiang, ZHENG, Tong, WANG, Fang, AI, Qin, HAN, Aijuan, WU, Xiong, CAO, Chao, LI, Xia, YIN, Mengyao, LIU   +8 more
core   +1 more source

Puerarin transport across a Calu-3 cell monolayer – an in vitro model of nasal mucosa permeability and the influence of paeoniflorin and menthol

, 2016
Lin Zhang, Shou-Ying Du, Yang Lu, Chang Liu, Zhi-Hao Tian, Chang Yang, Hui-Chao Wu, Zhen Wang School of Chinese Materia Medica, Beijing University of Chinese Medicine, Chaoyang District, Beijing, People’s Republic of China Abstract: Nasal ...
Wu HC, Du SY, Lu Y, Zhang L, Liu C, Tian ZH, Yang C, Wang Z   +7 more
core  

Biosynthesis of puerarin in Pueraria root.

Chemical and Pharmaceutical Bulletin, 1977
^ C-Labelled isoliquiritigenin was efficiently incorporated into puerarin of Pueraria lobata but 14C-labelled daidzein was almost not into it. These results support that the C-glycosylation occurs at the stage of chalcone or flavanone. Further competitive feeding experiments with T-or 14C-labelled isoliquiritigenin and liquiritigenin suggest that ...
INOUE, TAKAO, FUJITA, MASAO
openaire   +2 more sources

Cytoprotective Effect of Liposomal Puerarin on High Glucose-Induced Injury in Rat Mesangial Cells

, 2021
In diabetic patients, high glucose and high oxidative states activate gene expression of transforming growth factor beta (TGF-β) and further translocate Smad proteins into the nucleus of renal cells.
Ming-Fa Hsieh, Chu-Yin Chen, Jui-Ting Hsiao, Yu-Lung Chang, Lassina Barro   +4 more
core   +1 more source

Formulation and Pharmacokinetics Evaluation of Puerarin Nanocrystals for Intravenous Delivery

, 2012
Puerarin is a very widely used drug for treating coronary heart disease. Owing to its poor water solubility and the adverse drug reactions caused by cosolvents having been confirmed by SFDA, the aim of present study was to construction and evaluation the
Du, Yongli, Liu, Zhaoping, Zhang, Qiang, Zhang, Dianrui, Ma, Yi, Ma, Yingying, Ma, Vi, Wang, Yancai   +7 more
core   +1 more source

Puerarin attenuates S. aureus-induced mastitis through inhibiting inflammation and ferroptosis by activating the SIRT1/p53/SLC7A11 signaling pathway

Microbiology Spectrum
Mastitis, one of the most prevalent diseases in humans and animals, is commonly caused by local infection of the mammary gland. Puerarin inhibits mitochondrial oxidative stress and acute liver injury in mice.
Yang Yang, Liang Sun, Changlong Song, Di Zhou   +3 more
doaj   +1 more source

Puerarin Promotes the Migration and Differentiation of Myoblasts by Activating the FAK and PI3K/AKT Signaling Pathways

Biology
Puerarin, a flavonoid compound present in the roots of radix puerariae, contributes to the development of tissues such as bone and nerve, but its role in skeletal muscle regeneration remains unclear.
Xiaofeng Fang, Hangjia Xu, Zhaoxin Fan, Hongge Yang, Yan Huang, Lin Xu, Yiwei Rong, Wei Ma, Liubao Pei, Hongsheng Liang   +9 more
doaj   +1 more source

Puerarin Attenuates Cycloheximide-Induced Oxidative Damage and Memory-Consolidation Impairment in Rats

Journal of Integrative Neuroscience
Background: Cycloheximide (CXM), an antifungal antibiotic, causes impaired memory consolidation as a side effect partially by disturbing the activities of the central catecholaminergic and cholinergic system.
Kuo-Jen Wu, Jin-Cherng Lien, Chi-Rei Wu
doaj   +1 more source

Characterization of the molecular mechanisms underlying the neurotrophic and neuroprotective activities of puerarin

, 2015
Parkinson’ disease (PD) is a neurodegenerative disease characterized by the progressive loss of dopaminergic nigrostriatal neurons. Current anti-parkinsonism therapies mainly improve motor symptoms in PD patients.
Zhao, Jia, 趙佳
core   +1 more source

Dietary Puerarin Enhances Growth, Immune Function, Antioxidant Capacity, and Disease Resistance in Farmed Largemouth Bass, Micropterus salmoides

Fishes
Puerarin, a bioactive isoflavone extracted from Pueraria lobata, possesses well-documented pharmacological properties, including anti-inflammatory, antioxidant, and metabolic regulatory effects, which have been extensively studied in mammalian models and
Yi Huang, Wenjing Ma, Disen Zhang, Xi Chen, Zhiqiu Huang, Yuhang Hong   +5 more
doaj   +1 more source