Absolute oral bioavailability and disposition kinetics of puerarin in female rats
Background Pueraria candollei var. mirifica is a medicinal plant that is promoted as a “Champion Product” by the Government of Thailand. This plant has been reported to relieve postmenopausal symptoms, prevent and reverse bone loss, inhibit the growth of
Natthaphon Hunsakunachai +5 more
core +1 more source
STUDY ON THE SYNTHESIS OF PUERARIN DERIVATIVES AND THEIR ANTI-VASCULAR DEMENTIA ACTIVITY [PDF]
In this study, puerarin derivatives were designed by adding an active acetonitrile group that inhibits cyclooxygenase-2 (COX-2) in order to enhance the anti-vascular dementia drug activity.
Jiang, Pei
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White Pepper and Piperine Have Different Effects on Pharmacokinetics of Puerarin in Rats
This study attempted to explore the effects of white pepper and its major component piperine on puerarin administered to rats. Pharmacokinetic parameters of puerarin in rats were determined by oral administration (400 mg/kg) or intravenous injection (40 ...
Yong-Zhuo Liang +11 more
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Protective effects and mechanisms of puerarin in ovariectomized animal models of osteoporosis: a systematic review and meta-analysis of preclinical studies. [PDF]
Dong C +9 more
europepmc +1 more source
Puerarin attenuates polystyrene (PS-MPs) induced oxidative stress, apoptosis and DNA damage in a Rat model. [PDF]
Alqhtani EA +9 more
europepmc +1 more source
Renoprotective actions of puerarin and the prospects of kidney-targeted nanodelivery. [PDF]
Huang Y +11 more
europepmc +1 more source
Molecular Mechanisms and Therapeutic Potential of Puerariae Lobatae Radix in Bone Metabolism: A Comprehensive Review. [PDF]
Zhou Z, Li Y, Zou S, Wang A, Ni L, Lu J.
europepmc +1 more source
Dietary Puerarin Modulates the Rumen Microbiota and Enhances Growth Performance and Rumen Fermentation in Hu Sheep. [PDF]
Nie C +7 more
europepmc +1 more source
An Integrated Strategy for Decoding Bioactive Components and Mechanism of Jingtong Granules: Chemical Characterization, Network Analysis, Pharmacokinetic and Pharmacodynamic Studies. [PDF]
Liu J +10 more
europepmc +1 more source
Research Progress of Puerarin and Its Benefits in Nonalcoholic Fatty Liver Disease: A Bibliometric Analysis. [PDF]
Wang W, Liu X.
europepmc +1 more source

