Results 21 to 30 of about 1,417,462 (268)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Prior COVID‐19 infection among newly diagnosed tuberculosis patients in a tertiary care center in Tehran: A case‐control study

Immunity, Inflammation and Disease
Objective To assess the risk of developing pulmonary tuberculosis (TB) in accordance with prior history of COVID‐19 infection. Background Since the advent of the COVID‐19 pandemic much discussion has been had on the possible role it might play on global ...
Kiavash Semnani, Marjan Sohrabi, Parvaneh Ebrahimi Alavijeh, SeyedAhmad SeyedAlinaghi, Shirin Esmaeili, Farzin Halabchi, Zahra Alizadeh, Amir Salami, Arezoo Salami Khaneshan   +8 more
doaj   +1 more source

Cryotherapy in Egyptian patients with central airway obstruction: impacts on clinical pulmonary scores, pulmonary function tests and quality of life, a single center experience

Egyptian Journal of Chest Disease and Tuberculosis, 2023
Background Cryotherapy has emerged as an effective modality to manage patients with central airway obstruction (CAO). The aim was to assess the outcomes of using cryotherapy for managing CAO and its effect on the symptoms, and pulmonary function testing (
Ahmed Al Halfawy, Hassan Amin, Muhammad Younis, Usama E Abu Elhassan   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Genetic polymorphisms in lung disease: bandwagon or breakthrough?

Respiratory Research, 2002
The study of genetic polymorphisms has touched every aspect of pulmonary and critical care medicine. We review recent progress made using genetic polymorphisms to define pathophysiology, to identify persons at risk for pulmonary disease and to predict ...
Rybicki Benjamin, Maliarik Mary, Iannuzzi Michael C   +2 more
doaj   +1 more source

Awareness of chronic obstructive pulmonary disease (COPD) among the general population in Aseer Region, Kingdom of Saudi Arabia (KSA)

Journal of Family Medicine and Primary Care, 2023
Background: Chronic obstructive pulmonary disease (COPD) is a common but preventable disease and has a prevalence of 5%–14% in the general population. It is characterized by airflow limitation and persistent respiratory symptoms. In this survey, we aimed
Ali Al Bshabshe, Nawaf Al Shuqayfah, Fahad Alahmari, Abdulmalik Alhomrany, Nashwa M. Noreldin, Wesam F. Mousa, Abdullah Algarni   +6 more
doaj   +1 more source

Pulmonary Melioidosis

Chest, 1995
Melioidosis is the name given to all diseases caused by the bacterium Pseudomonas pseudomallei. Melioidosis is a tropical disease and prevails in parts of Southeast Asia, northern Australia, and Central and South America. However, in recent years, cases of melioidosis have been reported in the United States and other areas.
Osterberg, LG, Ip, M, Raffin, TA, Chau, PY   +3 more
openaire   +4 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

E-cigarette Health Effects on Major Body Systems: A Comprehensive Review of Cardiovascular, Respiratory, and Diabetic Implications

Journal of Education, Health and Sport
This systematic review examined the health implications of electronic cigarette (e-cigarette) use, focusing on cardiovascular, pulmonary, and metabolic effects through analysis of literature published between 2016 and 2023. The study utilized PubMed and
Jakub Tomaszewski, Martyna Borowska-Łygan, Rafał Wojciech Rejmak, Kornelia Karamus, Jan Biłogras, Konrad Strużek , Wojciech Urban   +6 more
doaj   +1 more source

Dilatation of the Pulmonary Artery in Pulmonary Stenosis [PDF]

Circulation, 1956
Dilatation of the pulmonary artery occurs frequently in cases of valvular pulmonary stenosis and is often called "poststenotic." We determined the diameter of the pulmonary artery angiocardiographically and compared this with the data obtained by heart catheterization in cases of pulmonary stenosis and of idiopathic dilatation of the pulmonary artery ...
openaire   +3 more sources