Results 41 to 50 of about 1,482,763 (269)

Isolated pulmonary involvement in Erdheim–Chester disease

Lung India, 2017
Erdheim–Chester disease is a rare non-Langerhans cell histiocytic disorder. It is primarily a disease of the long bones. Pulmonary involvement in systemic disease is detected in about half the reported cases.
Enambir Singh Josan, Jason W Green, Syed Imran M Zaidi, Jayantilal B Mehta   +3 more
doaj   +1 more source

Comparison of typical and atypical computed tomography patterns regarding reversibility and fibrosis in pulmonary sarcoidosis

Annals of Thoracic Medicine, 2021
PURPOSE: This study aims to investigate whether there is a significant difference between typical and atypical parenchymal patterns in the development of fibrosis, which is the most crucial factor affecting morbidity in pulmonary sarcoidosis. METHODS: In
Seher Susam, Fatma Demirci Ucsular, Enver Yalniz, Akin Cinkooglu, Gulru Polat, Berna Eren Komurcuoglu, Ceyda Anar, Gulistan Karadeniz, Ali Kadri Cirak, Emel Tellioglu, Filiz Guldaval, Mine Gayaf, Nimet Aksel, Ozgur Batum, Dursun Alizoroglu, Semra Bilaceroglu   +15 more
doaj   +1 more source

Pulmonary Melioidosis

Chest, 1995
Melioidosis is the name given to all diseases caused by the bacterium Pseudomonas pseudomallei. Melioidosis is a tropical disease and prevails in parts of Southeast Asia, northern Australia, and Central and South America. However, in recent years, cases of melioidosis have been reported in the United States and other areas.
Osterberg, LG, Ip, M, Raffin, TA, Chau, PY   +3 more
openaire   +4 more sources

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Pulmonary artery diameter to predict pulmonary hypertension in pulmonary sarcoidosis [PDF]

European Respiratory Journal, 2015
Pulmonary hypertension (PH) is a known complication of pulmonary sarcoidosis with a prevalence ranging from 5% to 74% [1]. The aetiology of PH in sarcoidosis is not fully understood. Usually, it is attributed to the destruction of the distal capillary bed by lung fibrosis and/or chronic hypoxaemia.
Marloes P, Huitema, Marcela, Spee, Veronique M M, Vorselaars, Sanne, Boerman, Repke J, Snijder, Hendrik W, van Es, Herre J, Reesink, Jan C, Grutters, Marco C, Post   +8 more
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

IDIOPATHIC PULMONARY HEMOSIDEROSIS. A CASE WITH AUTOIMMUNE DISEASE IN THE FAMILY [PDF]

Romanian Journal of Pediatrics, 2018
Idiopathic pulmonary hemosiderosis (IPH) is a chronic, recurrent pulmonary disease predominantly affecting children and often having severe outcome. The triad consisting in iron-deficiency anemia, hemoptysis and diffuse pulmonary infiltrates can guide ...
Catalina Bica, Ligia Georgeta Stanescu, Liana Cismaru, Radu Diaconu, Larisa Troi, Sorin Dinescu   +5 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source