Results 31 to 40 of about 1,417,462 (268)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Pulmonary hemorrhage in an outpatient ophthalmic anesthesia setting− it′s never "just a cataract"
Journal of Anaesthesiology Clinical Pharmacology, 2012 A 48-year-old man, with end stage renal disease and a history of recreational drug abuse, presented for elective cataract surgery. Patient underwent the procedure with a general endotracheal anesthesia with a balanced anesthetic.
Ashish K Khanna, Kenneth C Cummings
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Pulmonary AV fistula in bilateral pulmonary embolism with pulmonary hypertension [PDF]
Heart Asia, 2010 A 40-year male presented with complaints of dyspnoea on exertion of 6 months duration. Physical examination was unremarkable, and arterial oxygen saturation was 95%. ECG revealed sinus tachycardia with RV strain. Doppler lower-limb study showed significant thrombus burden in bilateral …
G, Shalima +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Primary Malignant Melanoma of the Lung: A Case Report
World Journal of Surgical Oncology, 2003 Background Primary melanoma of the lung is an extremely rare pathological entity and sparsely reported in the literature. Case presentation A case of primary malignant melanoma of the lung in a 41-year-old female is reported.
Karagianni Evangelia +3 more
doaj +1 more source
Pulmonary rehabilitation [PDF]
European Respiratory Review, 2014 Pulmonary rehabilitation is a comprehensive intervention designed to improve the physical and psychological condition of people with chronic respiratory disease and promote the long-term adherence to health-enhancing behaviours. During the 2013 European Respiratory Society Annual Congress in Barcelona, Spain, a Clinical Year in Review session was held ...
openaire +4 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Pulmonary alveolar microlithiasis with calcified pleural plaques
Lung India, 2010 Pulmonary alveolar microlithiasis (PAM) is a rare disease. Herein we report a case of pulmonary alveolar microlithiasis who was suspected to have the disease on chest X-ray and was confirmed on high resolution CT and transbronchial lung biopsy.
Malhotra Balbir +3 more
doaj
Single-Use and Reusable Flexible Bronchoscopes in Pulmonary and Critical Care Medicine
Diagnostics, 2022 Flexible bronchoscopy plays a critical role in both diagnostic and therapeutic management of a variety of pulmonary disorders in the bronchoscopy suite and the intensive care unit.
Elliot Ho +3 more
doaj +1 more source