Macrophage-epithelial interactions in pulmonary alveoli [PDF]
Alveolar macrophages have been investigated for years by approaches involving macrophage extraction from the lung by bronchoalveolar lavage, or by cell removal from lung tissue. Since extracted macrophages are studied outside their natural milieu, there is little understanding of the extent to which alveolar macrophages interact with the epithelium, or
Jahar Bhattacharya, Kristin Westphalen
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Hydrodynamic Cleansing of Pulmonary Alveoli [PDF]
The inside wall of the pulmonary alveolus is lined with a thin viscous fluid layer and a monolayer of surfactants. Inhaled foreign particles that reach the lung alveoli are normally neutralized by macrophages and remain inside the lung. Nevertheless, Podgorski and Gradon [Ann. Occup. Hyg., 37 (1993), pp.
Daphne Zelig, S. Haber
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ABSORPTION FROM THE PULMONARY ALVEOLI [PDF]
Experiments upon dogs anesthetized with nembutal and lasting 4 hours, in which the right lymphatic duct and thoracic duct have been cannulated and collection of lung lymph and blood specimens was accomplished after intratracheal instillation of dog plasma, purified bovine serum albumin, crystallized egg albumin, and hemoglobin, have shown that the ...
Cecil K. Drinker, Esther Hardenbergh
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Pulmonary Surfactant Function in Alveoli and Conducting Airways [PDF]
Surface tension plays a very important role in aeration of the neonate's lungs. Pulmonary surfactant, which is inadequate in the premature infant, modifies surface tension during the act of breathing and is necessary for maintenance of alveolar stability.
Goran Enhorning
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Keeping it together: Pulmonary alveoli are maintained by a hierarchy of cellular programs [PDF]
The application of in vivo genetic lineage tracing has advanced our understanding of cellular mechanisms for tissue renewal in organs with slow turnover, like the lung. These studies have identified an adult stem cell with very different properties than classically understood ones that maintain continuously cycling tissues such as the intestine.
Catriona Y. Logan, Tushar Desai
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Submicron particle deposition in pulmonary alveoli during cyclic breathing [PDF]
The prediction of deposition eciency of submicron particles in the pulmonary alveoli has received special attention due to its importance for drug delivery systems and for assessing air pollutants health risks. In this work, the pulmonary alveoli of a healthy human are idealized by a three-dimensional honeycomb-like conguration and a fluid-structure ...
Mojdeh Monjezi+2 more
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Growth of the alveoli and pulmonary arteries in childhood [PDF]
Since alveolar and airway growth have previously been studied in greater detail than has arterial growth, the present study establishes the growth pattern of the arteries and relates this to that of the alveoli and airways. The pattern of post-natal alveolar multiplication found is similar to that reported by Dunnill, but for all ages about 10% above ...
G. Davies, L. Reid
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Synchrotron x-ray imaging of pulmonary alveoli in respiration in live intact mice [PDF]
Despite nearly a half century of studies, it has not been fully understood how pulmonary alveoli, the elementary gas exchange units in mammalian lungs, inflate and deflate during respiration.
Soeun Chang+7 more
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Simultaneous three-dimensional optical coherence tomography and intravital microscopy for imaging subpleural pulmonary alveoli in isolated rabbit lungs [PDF]
There is a growing interest in analyzing lung mechanics at the level of the alveoli in order to understand stress-related pathogenesis and possibly avoid ventilator associated lung injury.
Sven Meißner+4 more
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Retinoic acid receptor-β: an endogenous inhibitor of the perinatal formation of pulmonary alveoli [PDF]
Pulmonary alveoli are formed, in part, by subdivision (septation) of the gas-exchange saccules of the immature lung.
Gloria De Carlo Massaro+6 more
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