Alveolar lipids in pulmonary disease. A review
Lung lipid metabolism participates both in infant and adult pulmonary disease. The lung is composed by multiple cell types with specialized functions and coordinately acting to meet specific physiologic requirements. The alveoli are the niche of the most
Christina W. Agudelo +2 more
doaj +1 more source
Retrospective Analysis of 61 Cases of Children Died of Viral Pneumonia [PDF]
Objective To retrospectively analyze the forensic pathological postmortem examination and clinical data of children who died of viral pneumonia in identification of cause of death cases and to discuss the clinical characteristics and pathological ...
CHEN Xue-bing, DU Si-hao, LU Jian-cong, et al
doaj +1 more source
Role Of Inhaled Nitric Oxides In Pregnancy With Eisenmenger Syndrome
Eisenmenger Syndrome (ES) is congenital heart disease with pulmonary hypertension and shunting turning from right to left. The resistance of pulmonary vascular more than 7.5 mmHg/L/min. The right ventricle and pulmonary artery always enlarge.
Muhammad Anas +2 more
doaj +1 more source
A mammalian Wnt5a-Ror2-Vangl2 axis controls the cytoskeleton and confers cellular properties required for alveologenesis. [PDF]
Alveolar formation increases the surface area for gas-exchange and is key to the physiological function of the lung. Alveolar epithelial cells, myofibroblasts and endothelial cells undergo coordinated morphogenesis to generate epithelial folds (secondary
Chou, Yu-Ting +7 more
core +1 more source
Management of Mechanical Ventilation in Decompensated Heart Failure. [PDF]
Mechanical ventilation (MV) is a life-saving intervention for respiratory failure, including decompensated congestive heart failure. MV can reduce ventricular preload and afterload, decrease extra-vascular lung water, and decrease the work of breathing ...
Adams, Jason Y +4 more
core +4 more sources
Platelet kinetics in the pulmonary microcirculation in vivo assessed by intravital microscopy [PDF]
Growing evidence supports the substantial pathophysiological impact of platelets on the development of acute lung injury. Methods for studying these cellular mechanisms in vivo are not present yet.
Eichhorn, M. E. +3 more
core +1 more source
Review of hypoxaemia in the anaesthetized horse: predisposing factors, consequences and management [PDF]
Objectives: To discuss how hypoxaemia might be harmful and why the horse is particularly predisposed to developing it. To review the strategies that are used to manage hypoxaemia in anaesthetised horses, to describe how successful these strategies are
Auckburally, Adam, Nyman, Görel
core +1 more source
Pulmonary alveolar type I cell population consists of two distinct subtypes that differ in cell fate. [PDF]
Pulmonary alveolar type I (AT1) cells cover more than 95% of alveolar surface and are essential for the air-blood barrier function of lungs. AT1 cells have been shown to retain developmental plasticity during alveolar regeneration.
Cai, Tao +11 more
core +1 more source
YAP regulates alveolar epithelial cell differentiation and AGER via NFIB/KLF5/NKX2-1
Summary: Ventilation is dependent upon pulmonary alveoli lined by two major epithelial cell types, alveolar type-1 (AT1) and 2 (AT2) cells. AT1 cells mediate gas exchange while AT2 cells synthesize and secrete pulmonary surfactants and serve as ...
Jason J. Gokey +6 more
doaj +1 more source
Pleiotropy as the Mechanism for Evolving Novelty: Same Signal, Different Result. [PDF]
In contrast to the probabilistic way of thinking about pleiotropy as the random expression of a single gene that generates two or more distinct phenotypic traits, it is actually a deterministic consequence of the evolution of complex physiology from the ...
Torday, John S
core +9 more sources

