Results 101 to 110 of about 285,607 (297)

Prognostic Value of the Persistence or Change in Pericardial Effusion Status on Serial Echocardiograms in Pulmonary Arterial Hypertension [PDF]

, 2013
Background: Pericardial effusion in pulmonary arterial hypertension (PAH) is an indicator of right heart failure and a marker of poor prognosis; its significance on serial transthoracic echocardiograms (TTE) is not clear.
Dardari, Zeina A.
core  

Riociguat for the treatment of chronic thromboembolic pulmonary hypertension. [PDF]

, 2013
BACKGROUND: Riociguat, a member of a new class of compounds (soluble guanylate cyclase stimulators), has been shown in previous clinical studies to be beneficial in the treatment of chronic thromboembolic pulmonary hypertension. METHODS: In this phase 3,
CHEST-1 Study Group,, D'Armini, AM, Fritsch, A, Ghofrani, HA, Grimminger, F, Hoeper, MM, Jansa, P, Kim, NH, Mayer, E, Neuser, D, Simonneau, G, Wang, C, Weimann, G, Wilkins, MR   +13 more
core   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Transmembrane protein 16A/anoctamin 1 inhibitor T16A-A01 reversed monocrotaline-induced rat pulmonary arterial hypertension

Pulmonary Circulation, 2020
Transmembrane protein 16A was involved in the development of the monocrotaline-induced pulmonary arterial hypertension model through ERK1/2 activation, and it was considered as potential target for pulmonary arterial hypertension treatment.
Jianye Xie, Wenyuan Liu, Wenjing Lv, Xiaohua Han, Qingnuan Kong, Yuhui Wu, Xin Liu, Ying Han, Chunying Shi, Xiujuan Jia   +9 more
doaj   +1 more source

Oestrogen receptor alpha in pulmonary hypertension [PDF]

, 2015
Aims Pulmonary arterial hypertension (PAH) occurs more frequently in women with mutations in bone morphogenetic protein receptor type 2 (BMPR2) and dysfunctional BMPR2 signalling underpinning heritable PAH.
Audrey F. Wright, Austin, Benza, Chambliss, Dempsie, Dempsie, Eddahibi, Huang, Humbert, Jala, Kawut, Keegan, Kirsty Mair, Lahm, Lindberg, Long, Long, Lynn Loughlin, Ma, Machado, MacLean, Mair, Margaret Nilsen, Margaret R. Maclean, Marie-Ann Ewart, Marino, Massaro, Massaro, Matori, Matsumoto, Mcgoon, Mendelsohn, Meyer, Meyer, Morani, Nadadur, Nilsson, Pattarozzi, Pedram, Pedram, Rajkumar, Roberts, Rubanyi, Ryu, Shapiro, Takahashi, Umar, Ventetuolo, White, White, White, Wu, Yang, Yvonne Dempsie   +53 more
core   +4 more sources

A Dynamic 3D Human Liver Sinusoid Model for Mechanistic Interrogation of Fontan‐Associated Liver Disease

Advanced Science, EarlyView.
This study presents a perfusable 3D bioengineered liver sinusoid platform that integrates biofabrication, 3D cell culture, controlled hemodynamics, and multiparametric characterization to model Fontan‐associated liver disease. By decoupling pressure and hypoxia effects, the system reveals early mechanobiological and profibrotic responses under ...
Sarah Rezapourdamanab, Mehdi Salar Amoli, Tanmay Mukherjee, Maryam Bagheri, Boeun Hwang, Linqi Jin, Yamini Singh, Sophia Norton, Ashay Vishwas Bongirwar, Shweta Karnik, Lakshmi Prasad Dasi, Reza Avazmohammadi, Rene Romero, Holly D. Bauser‐Heaton, Vahid Serpooshan   +14 more
wiley   +1 more source

Early Outcomes After Total Arch Replacement With Frozen Elephant Trunk in Elderly Patients With Acute Type A Aortic Dissection

AGING MEDICINE, EarlyView.
Across seven centers (2015–2023), we studied 1634 ATAAD patients undergoing TAR+FET and, after propensity matching (n = 699), compared elderly (≥ 60) versus non‐elderly (< 60) outcomes. Elderly patients had higher 30‐day mortality and complications (log‐rank p = 0.002), supporting individualized hybrid strategies, organ‐protective perioperative care ...
Jiajun Liang, Yuan Xue, Yeting Lou, Hao Han, Xiaohan Zhong, Zhou Liu, Tianxu Han, Meili Wang, Wenjian Jiang, Hongjia Zhang, Haiyang Li, Yuanfei Zhao   +11 more
wiley   +1 more source

Elevated serum levels of macrophage migration inhibitory factor and stem cell growth factor β in patients with idiopathic and systemic sclerosis associated pulmonary arterial hypertension. [PDF]

, 2015
Pulmonary arterial hypertension (PAH) can be idiopathic or secondary to autoimmune diseases, and it represents one of the most threatening complications of systemic sclerosis (SSc).
Alessandri, Cristiano, Badagliacca, Roberto, Pendolino, Monica, Poscia, Roberto, Riccieri, Valeria, Sciarra, Iliana, Stefanantoni, Katia, Valesini, Guido, Vasile, M, Vizza, Carmine Dario   +9 more
core   +2 more sources

Understanding pulmonary arterial hypertension

Nursing Management (Springhouse), 2004
New therapies improve the management of pulmonary arterial hypertension.
openaire   +4 more sources

Preoperative Aortic Calcification Volume Predicts Postoperative Complications in Nonpancreatic Cancer Patients Undergoing Pancreaticoduodenectomy

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background/Objectives Postoperative complications following pancreaticoduodenectomy (PD) remain high, particularly in patients with soft pancreatic texture. Abdominal aortic calcification volume (AACV), a surrogate marker of systemic arteriosclerosis, has been associated with increased surgical risk in lower gastrointestinal procedures ...
Masaki Horiuchi, Kentaro Miyake, Kota Sahara, Jun Yamamoto, Yutaro Kikuchi, Yasuhiro Yabushita, Yu Sawada, Yuki Homma, Ryusei Matsuyama, Itaru Endo   +9 more
wiley   +1 more source