Results 81 to 90 of about 1,381,406 (265)

Pharmacological treatment of pulmonary arterial hypertension

, 2018
Pulmonary arterial hypertension (PAH), characterized by increased pulmonary vascular resistance and arterial pressure,Pulmonary vasoconstriction and associated remodeling of the vascular walls are thought to be involved in the initiation of pulmonary ...
Almaghrabi, Abdullah
core  

Pulmonary arterial hypertension in limited cutaneous systemic sclerosis: a distinctive vasculopathy.

, 2009
Contains fulltext : 81797.pdf (Publisher’s version ) (Open Access)Systemic sclerosis-associated pulmonary arterial hypertension (SScPAH) has a worse prognosis and response to pulmonary arterial hypertension (PAH) therapy than idiopathic
Heijdra, Y.F., Heijdra, Y., Voskuyl, A.E., Vonk, M.C., Vonk Noordegraaf, A., Dijkmans, B.A., Grünberg, K., Smit, E.F., Vonk-Noordegraaf, A., Postmus, P.E., Overbeek, M.J., Dijkmans, B.A.C., Voskuijl, A.E., Boonstra, A., Mooi, W.J.   +14 more
core   +1 more source

Characteristics Associated With Persistent Long COVID Symptoms in Healthcare Personnel Infected With SARS‐CoV‐2 Between August 2022 and May 2024: A Multicenter Cohort Analysis of US Healthcare Personnel

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Long COVID affects a significant proportion of COVID‐19 survivors. This study examined persistent Long COVID symptoms among healthcare personnel (HCP) and evaluated associations with vaccination, prior SARS‐CoV‐2 infection, underlying health conditions, and demographics.
Eric Kontowicz, Amanda K. Irish, Lilly C. Lee, Howard A. Smithline, Ian D. Plumb, Melissa Briggs‐Hagen, Alexandra F. Rollins, Karisa K. Harland, Anusha Krishnadasan, Karin F. Hoth, Eliezer Santos‐León, David A. Talan, Nicholas M. Mohr, Project PREVENT Network   +13 more
wiley   +1 more source

A Case of Multiple Mitochondrial Dysfunctions Syndrome 1 and Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Multiple mitochondrial dysfunctions syndrome 1 (MMDS1, MIM #605711) due to NFU1 gene defects is an ultra‐rare autosomal recessive inborn error of metabolism associated with reduced function of NFU1 iron–sulfur cluster (ISC) scaffold protein.
Charles R. DiFalco, Aaron Williams, Claudia Soler‐Alfonso, Emily Waskow, Elizabeth Mizerik, Fernando Scaglia, Chaya N. Murali   +6 more
wiley   +1 more source

Establishing the diagnosis of 22q11.2 microdeletion syndrome in congenital heart disease is now an imperative

International Journal of Cardiology Congenital Heart Disease, 2021
Alexandra Arvanitaki, Michael A. Gatzoulis   +1 more
doaj   +1 more source

Effect of pulmonary hypertension on outcome of pulmonary tuberculosis

International Journal of Mycobacteriology, 2015
Objectives: Pulmonary hypertension is a serious disorder with catastrophic outcomes. This study aimed to evaluate the effect of pulmonary arterial hypertension on the outcome among new cases of pulmonary tuberculosis.
Majid Marjani, Payam Tabarsi, Parvaneh Baghaei, Afshin Moniri, Majid Malekmohammad   +4 more
doaj  

Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert, Gudny Anna Arnadottir, Laura Bedinger, Nicola Brunetti‐Pierri, Jennifer Cech, Xin Chen, Yanmin Chen, Erika Chick, Sarah Dyack, Madeleine Franchi, Tanja Frey, David Genevieve, Ian Glass, Jorge Granadillo, Kelly A. Keener, Sara B. MacKay, Paige McDunnah, Vinod K. Misra, Kristin G. Monaghan, Sureni V. Mullegama, Cristina Peduto, Leia Peterman‐Prather, Anita Rauch, Cherith Somerville, Kari Stefansson, Katharina Steindl, Patrick Sulem, Telma Sulem, Pamela Trapane, Roberta Zeuli, Samuel Zinner, Kosuke Izumi   +31 more
wiley   +1 more source

Plasma adrenomedullin peptides and precursor levels in pulmonary arterial hypertension disease severity and risk stratification

Pulmonary Circulation, 2020
Adrenomedullin is a potent vasodilatory peptide, linked to pulmonary arterial hypertension pathology. Proximity extension assays were utilized to study plasma biomarkers related to vasoregulation, with focus on adrenomedullin peptides and precursor ...
Habib Bouzina, Göran Rådegran
doaj   +1 more source

Tadalafil therapy for pulmonary arterial hypertension

, 2009
BACKGROUND: Treatment options for pulmonary arterial hypertension target the prostacyclin, endothelin, or nitric oxide pathways. Tadalafil, a phosphodiesterase type-5 inhibitor, increases cGMP, the final mediator in the nitric oxide pathway.
Frumkin, L., White, R. J., M. Chan, H. A. Ghofrani, L. Frumkin, B. H. Brundage, Beardsworth, A., Barst, R. J., A. Beardsworth, Galie, N., Z. Safdar, R. J. White, FEDELE, Francesco, Safdar, Z., G. Simonneau, Ghofrani, H. A., Shapiro, S., Simonneau, G., N. Galie, Oudiz, R. J., S. Shapiro, R. J. Oudiz, Chan, M., Brundage, B. H., T. O. Tadalafil Study Group: Response, Arterial Hypertension Pulmonary, R. J. Barst   +26 more
core   +1 more source

Non-invasive stroke volume assessment in patients with pulmonary arterial hypertension: left-sided data mandatory [PDF]

, 2008
Background Cardiovascular Magnetic Resonance (CMR) is an emerging modality in the diagnosis and follow-up of patients with Pulmonary Arterial Hypertension (PAH).
Mauritz, G.J., Mauritz Gert-Jan, Gert-Jan Mauritz, Anco Boonstra, Boonstra Anco, Vonk Noordegraaf, A., Marcus, J.T., Anton Vonk-Noordegraaf, Postmus Pieter E, Pieter E Postmus, Vonk-Noordegraaf Anton, Marcus J Tim, Westerhof Nico, J Tim Marcus, Postmus, P.E., Westerhof, N., Nico Westerhof, Boonstra, A.   +17 more
core   +2 more sources