Results 91 to 100 of about 194,414 (305)

Pulmonary Artery Denervation for Pulmonary Artery Hypertension

JACC: Cardiovascular Interventions, 2015
While the seminal advance in the treatment of pulmonary artery hypertension (PAH) over the past 2 decades has been pharmacological targeting of dysfunctional endothelium-derived pathways that contribute to the characteristic vascular remodeling of this condition irrespective of etiology [(1)][1],
openaire   +2 more sources

Pulmonary arterial hypertension in limited cutaneous systemic sclerosis: a distinctive vasculopathy.

, 2009
Contains fulltext : 81797.pdf (Publisher’s version ) (Open Access)Systemic sclerosis-associated pulmonary arterial hypertension (SScPAH) has a worse prognosis and response to pulmonary arterial hypertension (PAH) therapy than idiopathic
Heijdra, Y.F., Heijdra, Y., Voskuyl, A.E., Vonk, M.C., Vonk Noordegraaf, A., Dijkmans, B.A., Grünberg, K., Smit, E.F., Vonk-Noordegraaf, A., Postmus, P.E., Overbeek, M.J., Dijkmans, B.A.C., Voskuijl, A.E., Boonstra, A., Mooi, W.J.   +14 more
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Animal models of chronic thromboembolic pulmonary hypertension

Animal Models and Experimental Medicine, EarlyView.
Current animal models of CTEPH. Created using BioRender.com. Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, yet life‐threatening disorder characterized by persistent pulmonary vascular obstruction and elevated pulmonary artery pressure, with progressive remodeling and subsequent right heart failure.
Yong‐Jian Zhu, Lin‐Chao Zhou, Xiao‐Xue Zhang, Xiao‐Yang Ren, Yi Yan, Shao‐Fei Liu   +5 more
wiley   +1 more source

Pharmacological treatment of pulmonary arterial hypertension

, 2018
Pulmonary arterial hypertension (PAH), characterized by increased pulmonary vascular resistance and arterial pressure,Pulmonary vasoconstriction and associated remodeling of the vascular walls are thought to be involved in the initiation of pulmonary ...
Almaghrabi, Abdullah
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Tadalafil therapy for pulmonary arterial hypertension

, 2009
BACKGROUND: Treatment options for pulmonary arterial hypertension target the prostacyclin, endothelin, or nitric oxide pathways. Tadalafil, a phosphodiesterase type-5 inhibitor, increases cGMP, the final mediator in the nitric oxide pathway.
Frumkin, L., White, R. J., M. Chan, H. A. Ghofrani, L. Frumkin, B. H. Brundage, Beardsworth, A., Barst, R. J., A. Beardsworth, Galie, N., Z. Safdar, R. J. White, FEDELE, Francesco, Safdar, Z., G. Simonneau, Ghofrani, H. A., Shapiro, S., Simonneau, G., N. Galie, Oudiz, R. J., S. Shapiro, R. J. Oudiz, Chan, M., Brundage, B. H., T. O. Tadalafil Study Group: Response, Arterial Hypertension Pulmonary, R. J. Barst   +26 more
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Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

Right ventricular-pulmonary arterial coupling and pulmonary hypertension in hemodialysis: insights into structural cardiac changes and clinical implications

Renal Failure
Objectives This cross-sectional analysis from the CZecking Heart Failure in patients with advanced Chronic Kidney Disease trial (ISRCTN18275480) examined pulmonary hypertension and right ventricular-pulmonary arterial coupling in patients on chronic ...
Kristina Buryskova Salajova, Jan Malik, Lucie Kaiserova, Zuzana Hladinova, Zdenka Hruskova, Simona Janakova, Vladimir Tesar, Satu Sinikka Pesickova, Kristyna Michalickova, Katarina Rocinova, Barbora Szonowska, Anna Valerianova   +11 more
doaj   +1 more source

Long-term therapy of interferon-alpha induced pulmonary arterial hypertension with different PDE-5 inhibitors: a case report

Cardiovascular Ultrasound, 2005
background Interferon alpha2 is widely used in hepatitis and high-risk melanoma. Interferon-induced pulmonary arterial hypertension as a side effect is rare.
Baumann Gert, Sterry Wolfram, Eddicks Stephan, Hofmann Maja A, Borges Adrian C, Kiecker Felix, Jochmann Nicoline, Trefzer Uwe   +7 more
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Definitions and Diagnosis of Pulmonary Hypertension

, 2013
Pulmonary hypertension (PH) is defined by a mean pulmonary artery pressure ≥25 mm Hg at rest, measured during right heart catheterization. There is still insufficient evidence to add an exercise criterion to this definition.
Satoh, T., Bogaard, Harm Jan, Kurzyna, M., Wilkins, M.R., Frantz, R., Langleben, David, Khanna, Dinesh, Manes, Alessandra, Bogaard, H.J., Khanna, D., Badesch, David B., Hoeper, Marius M., Kurzyna, Marcin, Torres, F., Hoeper, M.M., Satoh, Toru, Wilkins, Martin R., Torres, Fernando, Condliffe, R., Langleben, D., Badesch, D.B., Frantz, Robert, Condliffe, Robin, Manes, A.   +23 more
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Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source