Results 111 to 120 of about 445,623 (380)

Regional and patient characteristic disparities in the outcomes of minimally invasive surgery for colorectal cancer in Japan

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This study aimed to clarify whether differences in minimally invasive surgery outcomes are associated with regional and patient characteristics. This study found regional and patient characteristic disparities in minimally invasive surgical outcomes; national policies should be implemented to address these inequities.
Atsushi Hamabe   +9 more
wiley   +1 more source

Cardiac sympathetic dysfunction in pulmonary arterial hypertension: lesson from left-sided heart failure

open access: yesPulmonary Circulation, 2019
Sympathetic nervous system hyperactivity has a well-recognized role in the pathophysiology of heart failure with reduced left ventricular ejection fraction.
Valentina Mercurio   +10 more
doaj   +1 more source

Automatic Pulmonary Artery-Vein Separation in CT Images using Twin-Pipe Network and Topology Reconstruction [PDF]

open access: yesarXiv, 2021
With the development of medical computer-aided diagnostic systems, pulmonary artery-vein(A/V) separation plays a crucial role in assisting doctors in preoperative planning for lung cancer surgery. However, distinguishing arterial from venous irrigation in chest CT images remains a challenge due to the similarity and complex structure of the arteries ...
arxiv  

Pulmonary Artery Denervation for Pulmonary Artery Hypertension

open access: yesJACC: Cardiovascular Interventions, 2015
While the seminal advance in the treatment of pulmonary artery hypertension (PAH) over the past 2 decades has been pharmacological targeting of dysfunctional endothelium-derived pathways that contribute to the characteristic vascular remodeling of this condition irrespective of etiology [(1)][1],
openaire   +3 more sources

Long-term therapy of interferon-alpha induced pulmonary arterial hypertension with different PDE-5 inhibitors: a case report

open access: yesCardiovascular Ultrasound, 2005
background Interferon alpha2 is widely used in hepatitis and high-risk melanoma. Interferon-induced pulmonary arterial hypertension as a side effect is rare.
Baumann Gert   +7 more
doaj   +1 more source

Hemodynamic assessment of pulmonary hypertension in mice: a model based analysis of the disease mechanism [PDF]

open access: yesarXiv, 2017
This study uses a one dimensional fluid dynamics arterial network model to infer changes in hemodynamic quantities associated with pulmonary hypertension in mice. Data for this study include blood flow and pressure measurements from the main pulmonary artery for 7 control mice with normal pulmonary function and 5 hypertensive mice with hypoxia induced ...
arxiv  

A Probabilistic Neural Twin for Treatment Planning in Peripheral Pulmonary Artery Stenosis [PDF]

open access: yesarXiv, 2023
The substantial computational cost of high-fidelity models in numerical hemodynamics has, so far, relegated their use mainly to offline treatment planning. New breakthroughs in data-driven architectures and optimization techniques for fast surrogate modeling provide an exciting opportunity to overcome these limitations, enabling the use of such ...
arxiv  

Clinical trial design and new therapies for pulmonary arterial hypertension

open access: yesEuropean Respiratory Journal, 2019
Until 20 years ago the treatment of pulmonary arterial hypertension (PAH) was based on case reports and small series, and was largely ineffectual. As a deeper understanding of the pathogenesis and pathophysiology of PAH evolved over the subsequent two ...
O. Sitbon   +9 more
semanticscholar   +1 more source

Gut microbiota modification suppresses the development of pulmonary arterial hypertension in an SU5416/hypoxia rat model

open access: yesPulmonary Circulation, 2020
The pathogenesis of pulmonary arterial hypertension is closely associated with dysregulated inflammation. Recently, abnormal alterations in gut microbiome composition and function were reported in a pulmonary arterial hypertension experimental animal ...
T. Sanada   +14 more
semanticscholar   +1 more source

Children With 22.Q.11.2 Deletion Syndrome: Sleep‐Disordered Breathing and Management

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Patients with 22q11.2 deletion syndrome (22q11DS) are predisposed to obstructive sleep apnea (OSA) due to an abnormal craniofacial anatomy with pharyngeal hypotonia, retrognathia, micrognathia, and glossoptosis. The aim of the study was to describe the prevalence and management of OSA in a cohort of children with 22q11DS.
Domenico Paolo La Regina   +6 more
wiley   +1 more source

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