Incident pulmonary arterial hypertension associated with Bosutinib
Pulmonary Circulation, 2020 Pulmonary arterial hypertension is associated with tyrosine kinase inhibitors used in the treatment of chronic myeloid leukemia. Dasatinib is a known cause of drug-induced pulmonary arterial hypertension.
Shaun Yo +3 more
doaj +1 more source
Quantification of Pulmonary Arterial Wall Distensibility Using Parameters Extracted from Volumetric Micro-CT Images [PDF]
, 1999 Stiffening, or loss of distensibility, of arterial vessel walls is among the manifestations of a number of vascular diseases including pulmonary arterial hypertension.
Dawson, Christopher A +3 more
core +2 more sources
Plasma proteome analysis in patients with pulmonary arterial hypertension: an observational cohort study [PDF]
, 2017 BackgroundIdiopathic and heritable pulmonary arterial hypertension form a rare but molecularly heterogeneous disease group. We aimed to measure and validate differences in plasma concentrations of proteins that are associated with survival in patients ...
Abdul-Salam +29 more
core +1 more source
European Respiratory Journal, 2019 Paediatric pulmonary arterial hypertension (PAH) shares common features of adult disease, but is associated with several additional disorders and challenges that require unique approaches.
E. Rosenzweig +7 more
semanticscholar +1 more source
Impact of the updated hemodynamic definitions on diagnosis rates of pulmonary hypertension
Pulmonary Circulation, 2020 We evaluated whether updated pulmonary hypertension definitive criteria proposed in sixth World Symposium on Pulmonary Hypertension had an impact on diagnosis of overall pulmonary hypertension and pre-capillary and combined pre- and post-capillary ...
Seda Tanyeri +15 more
doaj +1 more source
Animal Models of Pulmonary Arterial Hypertension and Their Application in Drug Research
Shiyan dongwu yu bijiao yixue, 2023 Pulmonary arterial hypertension is a clinical syndrome characterized by pulmonary vascular remodeling causing increased vascular resistance, which will lead to right heart failure and even death if left untreated.
YU Jiahui, GONG Qian, ZHUANG Lenan
doaj +1 more source
Sex and gender in pulmonary arterial hypertension
European Respiratory Review, 2021 Pulmonary arterial hypertension (PAH) is a rare disease characterised by pulmonary vascular remodelling and elevated pulmonary pressure, which eventually leads to right heart failure and death. Registries worldwide have noted a female predominance of the
Céline Cheron +11 more
semanticscholar +1 more source
Clinical heterogeneity of Pulmonary Arterial Hypertension associated with variants in TBX4.
PLoS ONE, 2020 BACKGROUND:The knowledge of hereditary predisposition has changed our understanding of Pulmonary Arterial Hypertension. Genetic testing has been widely extended and the application of Pulmonary Arterial Hypertension specific gene panels has allowed its ...
Ignacio Hernandez-Gonzalez +15 more
doaj +1 more source
Transcription factors and potential therapeutic targets for pulmonary hypertension
Frontiers in Cell and Developmental Biology, 2023 Pulmonary hypertension (PH) is a refractory and fatal disease characterized by excessive pulmonary arterial cell remodeling. Uncontrolled proliferation and hypertrophy of pulmonary arterial smooth muscle cells (PASMCs), dysfunction of pulmonary arterial ...
Liu Yang +5 more
doaj +1 more source
Matrix metalloproteinase 7 in diagnosis and differentiation of pulmonary arterial hypertension
Pulmonary Circulation, 2019 Pulmonary arterial hypertension is a severe disease for which diagnosis often is delayed. Matrix metalloproteinases have been suggested to play a role in vascular remodeling and pulmonary hypertension development. Our aim was therefore to investigate the
Mattias Arvidsson +3 more
doaj +1 more source