Results 51 to 60 of about 23,513 (181)

Atypical Clinical Course of Griscelli Syndrome Type 2 With Primarily Neurologic Presentation and Adult‐Onset in a 46‐Year‐Old Male

American Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1850-1855, August 2026.
ABSTRACT Griscelli Syndrome Type 2 (GS2) is a rare autosomal recessive disorder caused by pathogenic mutations in the RAB27A gene. Typically, it is characterized by cutaneous hypopigmentation, immunodeficiency, with or without neurological abnormalities secondary to hemophagocytic lymphohistiocytosis (HLH). Without treatment, GS2 often results in fatal
Dzhoy Papingi, Michael Kutsche, Helena Lichtenfeld, Fanny Kortüm, Angela Abicht, Laura Herrmann, Theresia Herget   +6 more
wiley   +1 more source

Neonatal Bloodstream Infections: A Narrative Review on Diagnostic and Therapeutic Challenges and Prospects in Developing Countries

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Bloodstream infections (BSIs) pose a significant global health challenge, particularly in developing countries. Neonates are highly vulnerable due to underdeveloped immune systems and immature physical barriers, a risk amplified by poor hygiene and limited healthcare access in low‐ and middle‐income countries (LMICs), leading to an ...
Alex Odoom, Abdul‐Halim Osman, Onyansaniba K. Ntim, Fleischer C. N. Kotey, Eric S. Donkor   +4 more
wiley   +1 more source

Infection Incidence and Survival in Patients With Multiple Myeloma and Chronic Lymphocytic Leukaemia: A Growing Concern in the Era of Modern Therapies

eJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Introduction Patients with multiple myeloma (MM) and chronic lymphocytic leukaemia (CLL) are burdened by immunodeficiency due to treatment and underlying disease. Infection‐related mortality remains a significant concern for patients' overall survival (OS). Methods This Swedish, population‐based study examined incidence of infections and OS in
Ingrid Glimelius, Love Tätting, Jonatan Freilich, M. Natalia Stelmaszuk, Qian Yang, Anna Deleskog, Sigurður Y. Kristinsson   +6 more
wiley   +1 more source

Pulmonary Aspergillosis: An Evolving Challenge for Diagnosis and Treatment

Infectious Diseases and Therapy, 2020
Aspergillus is a mold that may lead to different clinical pictures, from allergic to invasive disease, depending on the patient’s immune status and structural lung diseases.
Alessandro Russo, Giusy Tiseo, Marco Falcone, Francesco Menichetti   +3 more
doaj   +1 more source

Bronchoscopic Removal of Aspergilloma in a 26‐Year‐Old Man

Respirology Case Reports, Volume 14, Issue 8, August 2026.
A 26‐year‐old man with posttuberculous aspergilloma and a prior contralateral pneumonectomy remained refractory to voriconazole but was ineligible for surgery. The friable fungal ball was fragmented and completely extracted bronchoscopically over two sessions using progressively larger bronchoscopes, forceps, a Fogarty catheter and suction.
Chun‐Hao Wang, Lih‐Yu Chang, Jann‐Yuan Wang   +2 more
wiley   +1 more source

The Role of Invasive Procedures in the Treatment of Complicated Gastrointestinal Graft‐Versus‐Host Disease in Pediatric Patients

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti, Giorgio Persano, Chiara Grimaldi, Pier Luigi Di Paolo, Carmen Malaspina, Francesco Quagliarella, Valerio Balassone, Anna Chiara Iolanda Contini, Gian Luigi Natali, Rita Alaggio, Ivan Pietro Aloi, Tamara Caldaro, Alessandro Crocoli   +12 more
wiley   +1 more source

Inflammation‐driven variability in drug metabolism: Insights from voriconazole treatment of HSCT recipients

British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2250-2259, July 2026.
Aims Voriconazole is commonly used to prevent fungal infections after haematopoietic stem cell transplantation (HSCT). Although its metabolism is influenced by CYP2C19 genetics and inflammation, their combined effect is rarely considered in clinical practice, and integrated analyses remain limited.
Sylvia D. Klomp, Martijn L. Manson, Henk‐Jan Guchelaar, Stefan Böhringer, Esther H. M. van Egmond, Peter A. von dem Borne, Jesse J. Swen   +6 more
wiley   +1 more source

A case of pulmonary aspergillosis masquerading as pulmonary tuberculosis in a patient with type 2 diabetes mellitus [PDF]

Journal of Krishna Institute of Medical Sciences University
Patients with diabetes are more susceptible to infections than non-diabetics and often have severe clinical manifestations. The underlying immune dysregulations in these patients result in them developing serious, life-threatening infections.
Sidharth Shankar Panigrahi, Jayshree Swain, Vejendla S Srinivas, K. Lavanya, Teli Brij Rajesh   +4 more
doaj  

Inappropriate treatment of pulmonary aspergillosis caused by Aspergillus flavus in susceptible pediatric patients: a case series

Journal of Medical Case Reports
Background Pulmonary aspergillosis is a prevalent opportunistic fungal infection that can lead to mortality in pediatric patients with underlying immunosuppression.
Neginsadat Hosseinikargar, Hossein Zarrinfar, Seyed Javad Seyedi, Seyedeh Sabereh Mojtahedi   +3 more
doaj   +1 more source

Surgery in pulmonary aspergillosis

The Journal of Thoracic and Cardiovascular Surgery, 1975
Pulmonary aspergillosis is a rare disease, most commonly presenting as secondary invasion of pre-existing cavitary disease. In Toronto General Hospital 24 patients have been recognized as having this disorder in the 10 years from 1965 to 1975. The most common presenting symptoms were cough, sputum production, and hemoptysis, with the hemoptysis ...
R D, Henderson, J, Deslaurier, E L, Ritcey, N C, Delarue, F G, Pearson   +4 more
openaire   +2 more sources