Results 61 to 70 of about 1,252,486 (261)

Cryptococcus neoformans chitin synthase 3 plays a critical role in dampening host inflammatory responses [PDF]

, 2020
Cryptococcus neoformans is the most common disseminated fungal pathogen in AIDS patients, resulting in ∼200,000 deaths each year. There is a pressing need for new treatments for this infection, as current antifungal therapy is hampered by toxicity and/or
Hole, Camaron R, Lam, Woei C, Lodge, Jennifer K, Upadhya, Rajendra   +3 more
core   +2 more sources

NLRP3, NLRC4 and NLRC5 Gene Polymorphisms Associate with Susceptibility of Pulmonary Aspergillosis in Non-Neutropenic Patients

Journal of Clinical Medicine, 2022
Background: Non-neutropenic pulmonary aspergillosis is one of the most common and serious fungal infections. Previous studies have shown that single nucleotide polymorphisms (SNPs) of pattern recognition receptors genes are associated with susceptibility
J. Zhong, Lulu Liu, Yajie Lu, Y. Gu, Jiangnan Zhao, Bilin Chen, Wei Zhou, X. Su   +7 more
semanticscholar   +1 more source

Galactomannan-Antigen Testing from Non-Directed Bronchial Lavage for Rapid Detection of Invasive Pulmonary Aspergillosis in Critically Ill Patients: A Proof-of-Concept Study

Diagnostics, 2023
Invasive pulmonary aspergillosis is associated with high mortality. For diagnosis, galactomannan-antigen in serum and bronchoalveolar lavage fluid is recommended, with higher sensitivity in bronchoalveolar lavage fluid.
Kathrin Rothe, Miriam Dibos, Stefanie J. Haschka, Roland M. Schmid, Dirk Busch, Sebastian Rasch, Tobias Lahmer   +6 more
doaj   +1 more source

Cannabis and the lung [PDF]

, 2010
The use of cannabis is embedded within many societies, mostly used by the young and widely perceived to be safe. Increasing concern regarding the potential for cannabis to cause mental health effects has dominated cannabis research and the potential ...
Macleod, J, Reid, P T, Robertson, Roy
core   +1 more source

Nebulised surface-active hybrid nanoparticles of voriconazole for pulmonary Aspergillosis demonstrate clathrin-mediated cellular uptake, improved antifungal efficacy and lung retention

Journal of Nanobiotechnology, 2021
Background Incidence of pulmonary aspergillosis is rising worldwide, owing to an increased population of immunocompromised patients. Notable potential of the pulmonary route has been witnessed in antifungal delivery due to distinct advantages of direct ...
Ranjot Kaur, S. Dennison, A. J. Burrow, S. Rudramurthy, R. Swami, Varun Gorki, O. Katare, Anupama Kaushik, Bhupinder Singh, K. Singh   +9 more
semanticscholar   +1 more source

Invasive pulmonary mucormycosis and aspergillosis in a patient with decompensated hepatic cirrhosis

Medical Mycology Case Reports, 2018
Invasive pulmonary mucormycosis and aspergillosis are rare, life-threatening fungal infections. Most documented cases have been reported in non-cirrhotic patients with diabetes mellitus, neutropenia, or treatment with corticosteroids.
Jon G. Persichino, Argun D. Can, Tam T. Van, Michele N. Matthews, Scott G. Filler   +4 more
doaj   +1 more source

COVID-19 associated with pulmonary aspergillosis: A literature review

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2020
Bacterial or virus co-infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported in many studies, however, the knowledge on Aspergillus co-infection among patients with coronavirus disease 2019 (COVID-19) was limited.
Chih-Cheng Lai, Wen-Liang Yu
semanticscholar   +1 more source

Aspergillus Lateral Flow Assay with Digital Reader for the Diagnosis of COVID-19-Associated Pulmonary Aspergillosis (CAPA): a Multicenter Study

Journal of Clinical Microbiology, 2021
This multicenter study evaluated the IMMY Aspergillus Galactomannan Lateral Flow Assay (LFA) with automated reader for diagnosis of pulmonary aspergillosis in patients with COVID-19-associated acute respiratory failure (ARF) requiring intensive care unit
B. Autier, J. Prattes, P. White, M. Valerio, M. Machado, Jessica S. Price, M. Egger, J. Gangneux, M. Hoenigl   +8 more
semanticscholar   +1 more source

Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis. [PDF]

, 2020
There are limited treatment options for immunosuppressed patients with lethal invasive fungal infections due to Fusarium and Scedosporium Manogepix (MGX; APX001A) is a novel antifungal that targets the conserved Gwt1 enzyme required for localization of ...
Alkhazraji, Sondus, Alqarihi, Abdullah, Gebremariam, Teclegiorgis, Gu, Yiyou, Ibrahim, Ashraf S, Mamouei, Zeinab, Shaw, Karen J, Singh, Shakti, Wiederhold, Nathan P   +8 more
core   +1 more source

Microsatellite typing of avian clinical and environmental isolates of Aspergillus fumigatus [PDF]

, 2011
Aspergillosis is one of the most common causes of death in captive birds. Aspergillosis in birds is mainly caused by Aspergillus fumigatus, a ubiquitous and opportunistic saprophyte.
Beernaert, Lies, Dorrestein, Gerry M, Haesebrouck, Freddy, Klaassen, Corné HW, Martel, An, Pasmans, Frank, Van Waeyenberghe, Lieven, Vercammen, Francis, Verstappen, Frank   +8 more
core   +3 more sources