Results 61 to 70 of about 1,253,674 (265)

Invasive pulmonary mucormycosis and aspergillosis in a patient with decompensated hepatic cirrhosis

Medical Mycology Case Reports, 2018
Invasive pulmonary mucormycosis and aspergillosis are rare, life-threatening fungal infections. Most documented cases have been reported in non-cirrhotic patients with diabetes mellitus, neutropenia, or treatment with corticosteroids.
Jon G. Persichino, Argun D. Can, Tam T. Van, Michele N. Matthews, Scott G. Filler   +4 more
doaj   +1 more source

NLRP3, NLRC4 and NLRC5 Gene Polymorphisms Associate with Susceptibility of Pulmonary Aspergillosis in Non-Neutropenic Patients

Journal of Clinical Medicine, 2022
Background: Non-neutropenic pulmonary aspergillosis is one of the most common and serious fungal infections. Previous studies have shown that single nucleotide polymorphisms (SNPs) of pattern recognition receptors genes are associated with susceptibility
J. Zhong, Lulu Liu, Yajie Lu, Yu Gu, Jiangnan Zhao, Bilin Chen, Wei Zhou, X. Su   +7 more
semanticscholar   +1 more source

In Vitro Pharmacokinetic/Pharmacodynamic Modeling of Voriconazole Activity against Aspergillus Species in a New In Vitro Dynamic Model [PDF]

, 2012
The pharmacodynamics (PD) of voriconazole activity against Aspergillus spp. were studied using a new in vitro dynamic model simulating voriconazole human pharmacokinetics (PK), and the PK-PD data were bridged with human drug exposure to assess the ...
Zerva, Loukia, Meletiadis, Joseph, Velegraki, Aristea, Elefanti, Antigoni, Al Saigh, Rafal   +4 more
core   +1 more source

Special Issue:Chronic Pulmonary Aspergillosis

, 2022
I would like to thank all authors who contributed to this Journal of Fungi Special Issue on Chronic Pulmonary Aspergillosis (CPA) [...
Kosmidis, Chris, Kosmidis, Chris; id_orcid, Chris Kosmidis   +2 more
core   +1 more source

COVID-19 associated with pulmonary aspergillosis: A literature review

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2020
Bacterial or virus co-infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported in many studies, however, the knowledge on Aspergillus co-infection among patients with coronavirus disease 2019 (COVID-19) was limited.
Chih-Cheng Lai, Wen-Liang Yu
semanticscholar   +1 more source

Influenza- and COVID-19-Associated Pulmonary Aspergillosis: Are the Pictures Different?

Journal of Fungi, 2021
Invasive pulmonary aspergillosis (IPA) in intensive care unit patients is a major concern. Influenza-associated acute respiratory distress syndrome (ARDS) and severe COVID-19 patients are both at risk of developing invasive fungal diseases.
F. Reizine, Kieran Pinceaux, M. Lederlin, B. Autier, H. Guegan, Arnaud Gacouin, David Luque-Paz, C. Boglione-Kerrien, A. Bacle, Brendan Le Daré, Y. Launey, M. Lesouhaitier, B. Painvin, C. Camus, A. Mansour, F. Robert-Gangneux, S. Belaz, Y. le Tulzo, J. Tadié, A. Maamar, J. Gangneux   +20 more
semanticscholar   +1 more source

Pharmacodynamic Effects of Simulated Standard Doses of Antifungal Drugs against Aspergillus Species in a New In Vitro Pharmacokinetic/Pharmacodynamic Model [PDF]

, 2011
In conventional MIC tests, fungi are exposed to constant drug concentrations, whereas in vivo, fungi are exposed to changing drug concentrations.
Thomas J. Walsh, Emmanuel Roilides, Aristea Velegraki, Walsh, Thomas, Zerva, Loukia, Meletiadis, Joseph, Joseph Meletiadis, Roilides, Emmanuel, Rafal Al-Saigh, Velegraki, Aristea, Loukia Zerva, Al Saigh, Rafal   +11 more
core   +1 more source

Pulmonary aspergillosis associated with antineutrophil cytoplasmic antibody-positive vasculitis involving skin and peripheral nerves

Journal of the Indian Academy of Geriatrics
Invasive pulmonary aspergillosis is the most common cause of invasive fungal infection. Vasculitis secondary to bacterial, fungal, viral, and parasitic infections is documented in the literature.
Abhijith Rajaram Rao, Mohamed Rishan, Prakruthi Jaladhar, Prabha Adhikari   +3 more
doaj   +1 more source

Inflammation‐driven variability in drug metabolism: Insights from voriconazole treatment of HSCT recipients

British Journal of Clinical Pharmacology, EarlyView.
Aims Voriconazole is commonly used to prevent fungal infections after haematopoietic stem cell transplantation (HSCT). Although its metabolism is influenced by CYP2C19 genetics and inflammation, their combined effect is rarely considered in clinical practice, and integrated analyses remain limited.
Sylvia D. Klomp, Martijn L. Manson, Henk‐Jan Guchelaar, Stefan Böhringer, Esther H. M. van Egmond, Peter A. von dem Borne, Jesse J. Swen   +6 more
wiley   +1 more source

Nebulised surface-active hybrid nanoparticles of voriconazole for pulmonary Aspergillosis demonstrate clathrin-mediated cellular uptake, improved antifungal efficacy and lung retention

Journal of Nanobiotechnology, 2021
Background Incidence of pulmonary aspergillosis is rising worldwide, owing to an increased population of immunocompromised patients. Notable potential of the pulmonary route has been witnessed in antifungal delivery due to distinct advantages of direct ...
Ranjot Kaur, S. Dennison, A. J. Burrow, S. Rudramurthy, R. Swami, Varun Gorki, O. Katare, Anupama Kaushik, Bhupinder Singh, K. Singh   +9 more
semanticscholar   +1 more source