Results 71 to 80 of about 40,707 (252)

Fatal Invasive Aspergillosis and Coronavirus Disease in an Immunocompetent Patient

Emerging Infectious Diseases, 2020
Invasive pulmonary aspergillosis is a complication in critically ill patients with acute respiratory distress syndrome, especially those with severe influenza pneumonia.
Marion Blaize, Julien Mayaux, Cécile Nabet, Alexandre Lampros, Anne-Geneviève Marcelin, Marc Thellier, Renaud Piarroux, Alexandre Demoule, Arnaud Fekkar   +8 more
doaj   +1 more source

Using Interleukin 6 and 8 in Blood and Bronchoalveolar Lavage Fluid to Predict Survival in Hematological Malignancy Patients With Suspected Pulmonary Mold Infection. [PDF]

, 2019
Background: Molds and other pathogens induce elevated levels of several cytokines, including interleukin (IL)-6 and IL-8. The objective of this study was to investigate the prognostic value of IL-6 and IL-8 as well as fungal biomarkers in blood and ...
Eigl, Susanne, Flick, Holger, Heldt, Sven, Hoenigl, Martin, Jenks, Jeffrey D, Krause, Robert, Neumeister, Peter, Prattes, Juergen, Prüller, Florian, Rabensteiner, Jasmin, Rawlings, Stephen A, Strohmaier, Heimo, Wölfler, Albert   +12 more
core   +1 more source

Treatment outcomes in sinonasal aspergillosis in dogs in the United Kingdom: 436 cases (2011‐2021)

Journal of Small Animal Practice, EarlyView.
Objectives A variety of treatment options for sinonasal aspergillosis have been described, encompassing non‐invasive and invasive approaches. To describe the clinical outcomes in dogs treated for sinonasal aspergillosis in the United Kingdom. Materials and Methods A multi‐centre retrospective survey was performed involving 23 referral centres in the ...
C. D. Prior, H. Swales, A. Kortum, N. Reed, M. Sharman, D. Kelly, A. Kent, B. Glanemann, K. Clarke, C. Lea, E. Roberts, N. Bommer, L. Rutherford, A. Tamborini, K. Murphy, D. J. Batchelor, S. Calleja, R. Burrow, P. M. Jamieson, C. Piazza, M. Best, I. Calvo Saiz, I. Elgueta, S. J. Fowlie, C. Shales, C. Gil Morales, E. Lopez, S. Borgonovi, M. Keane, J. Kennils, E. Izaguirre, M. Hernandez‐Perello, N. Lau, A. Paul, A. Ridyard, E. Shelton, A. Farges, G. Specchia, L. Espada, S. Spence, A. Hrovat, N. Van den Steen, S. Tappin, T. H. Sparks, F. Allerton   +44 more
wiley   +1 more source

Primary intestinal aspergillosis resulting in acute intestinal volvulus after autologous stem cell transplantation in a patient with relapsed non-Hodgkin lymphoma : report on a rare infectious complication and a review of the literature

, 2019
Objectives: Since primary intestinal aspergillosis is a severe infectious complication with a high morbidity and mortality in immunocompromised patients, we want to draw attention to this rare entity and the importance of early recognition.
Kennes, Soetkin, Kerre, Tessa, Van de Putte, Dirk, Van Dorpe, Jo, VAN HENDE, VANESSA, Vlummens, Philip   +5 more
core   +1 more source

APX001 Is Effective in the Treatment of Murine Invasive Pulmonary Aspergillosis. [PDF]

, 2019
Invasive pulmonary aspergillosis (IPA) due to Aspergillus fumigatus is a serious fungal infection in the immunosuppressed patient population. Despite the introduction of new antifungal agents, mortality rates remain high, and new treatments are needed ...
Alkhazraji, Sondus, Alqarihi, Abdullah, Gebremariam, Teclegiorgis, Gu, Yiyou, Ibrahim, Ashraf S, Jeon, Heewon H, Kapoor, Mili, Shaw, Karen J   +7 more
core  

Mapping Bullous Emphysema With Lung Ultrasound: A Prospective Multicentre Study

Respirology, EarlyView.
ABSTRACT Background and Objectives Lung ultrasound holds high diagnostic performance for pleural diseases, notably pneumothorax. Bullous emphysema is a potential differential diagnosis of pneumothorax on ultrasound, but its precise semiology is poorly known.
Kinan El Husseini, Thomas Flament, Sophie Laroumagne, Damien Basille, Mathilde Le Brun, Elise Noël‐Savina, Philippe Richard, Gilles Mangiapan, Elise Artaud‐Macari   +8 more
wiley   +1 more source

Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis. [PDF]

, 2020
There are limited treatment options for immunosuppressed patients with lethal invasive fungal infections due to Fusarium and Scedosporium Manogepix (MGX; APX001A) is a novel antifungal that targets the conserved Gwt1 enzyme required for localization of ...
Alkhazraji, Sondus, Alqarihi, Abdullah, Gebremariam, Teclegiorgis, Gu, Yiyou, Ibrahim, Ashraf S, Mamouei, Zeinab, Shaw, Karen J, Singh, Shakti, Wiederhold, Nathan P   +8 more
core   +1 more source

Aspergillus After Lung Transplantation: Prophylaxis, Risk Factors, and the Impact on Chronic Lung Allograft Dysfunction

Transplant Infectious Disease, EarlyView.
Out of 274 lung transplant (LTx) patients, 89 (32%) developed invasive aspergillosis IA. Factors associated with IA were mycophenolate mofetil use, airway stenosis, Aspergillus cultured pre‐LTx, chronic lung allograft dysfunction (CLAD), and acute rejection. The role of nebulized amphotericin B and statins for prevention of IA remains unclear. ABSTRACT
Johanna P. van Gemert, Ger Jan Fleurke, Onno W. Akkerman, C. Tji. Gan, Willie N. Steenhuis, Huib A. M. Kerstjens, Erik A. M. Verschuuren, Douwe F. Postma   +7 more
wiley   +1 more source

Pattern recognition receptors in antifungal immunity [PDF]

, 2014
We thank the Wellcome Trust for funding this study.Peer reviewedPublisher ...
Brown, Gordon D, Hardison, Sarah E, Plato, Anthony   +2 more
core   +2 more sources

The Challenge of Bacterial Infections During Intensive Care Unit Stay After Heart Transplantation

Transplant Infectious Disease, EarlyView.
Abstract Background Infections occurring in the early post–heart transplant (HT) period heavily contribute to morbidity and mortality. Our goal is to evaluate the incidence of hospital‐acquired pneumonia/ventilator‐associated pneumonia (HAP/VAPs) and/or bloodstream infections (BSIs) after HT during the intensive care unit (ICU) stay and identify their ...
Rita Minucci, Annalisa De Silvestri, Patrizia Cambieri, Marta Corbella, Carlo Pellegrini, Silvia Roda, Chiara Dezza, Stefano Pelenghi, Raffaele Bruno, Mirko Belliato, Elena Seminari   +10 more
wiley   +1 more source