Results 51 to 60 of about 2,069,003 (398)

Parameter inference in a computational model of hemodynamics in pulmonary hypertension [PDF]

open access: yesarXiv, 2021
Pulmonary hypertension (PH), defined by a mean pulmonary arterial pressure (mPAP) $>$ 20 mmHg, is characterized by increased pulmonary vascular resistance and decreased pulmonary arterial compliance. There are few measurable biomarkers of PH progression, but a conclusive diagnosis of the disease requires invasive right heart catheterization (RHC ...
arxiv  

The efficacy and safety of pulmonary vasodilators in patients with Fontan circulation: a meta-analysis of randomized controlled trials

open access: yesPulmonary Circulation, 2018
No previous meta-analysis has evaluated the efficacy and safety of pulmonary vasodilators in Fontan physiology. Recent relative trials have obtained conflicting results regarding improvements in peak oxygen consumption; the relatively small number of ...
Wuwan Wang   +9 more
semanticscholar   +1 more source

Stochastic Simulation of Human Pulmonary Blood Flow and Transit Time Frequency Distribution Based on Anatomic and Elasticity Data [PDF]

open access: yes, 2012
The objective of our study was to develop a computing program for computing the transit time frequency distributions of red blood cell in human pulmonary circulation, based on our anatomic and elasticity data of blood vessels in human lung.
Jun Shi, R. T. Yen, Wei Huang
core   +2 more sources

Sex differences in the pulmonary circulation: implications for pulmonary hypertension.

open access: yesAmerican Journal of Physiology. Heart and Circulatory Physiology, 2014
Pulmonary arterial hypertension (PAH), a form of pulmonary hypertension, is a complex disease of multifactorial origin. While new developments regarding pathophysiological features and therapeutic options in PAH are being reported, one important fact has
Y. Martin, C. Pabelick
semanticscholar   +1 more source

Use of a right ventricular continuous flow pump to validate the distensible model of the pulmonary vasculature [PDF]

open access: yes, 2019
In the pulmonary circulation, resistive and compliant properties overlap in the same vessels. Resistance varies nonlinearly with pressure and flow; this relationship is driven by the elastic properties of the vessels. Linehan et al. (1982) correlated the
BovĂ©, Thierry   +5 more
core   +2 more sources

Fulvine and the pulmonary circulation [PDF]

open access: yesThorax, 1971
The pyrrolizidine alkaloid, fulvine, is now accepted as a major cause of veno-occlusive disease of the liver in the West Indies, where it is ingested as a decoction of the plant Crotalaria fulva in bush tea. Fulvine is similar in chemical structure to monocrotaline, which is known to cause pulmonary hypertension in rats.
Paul Smith   +4 more
openaire   +3 more sources

Noninvasive Estimation of Mean Pulmonary Artery Pressure Using MRI, Computer Models, and Machine Learning [PDF]

open access: yesarXiv, 2023
Pulmonary Hypertension (PH) is a severe disease characterized by an elevated pulmonary artery pressure. The gold standard for PH diagnosis is measurement of mean Pulmonary Artery Pressure (mPAP) during an invasive Right Heart Catheterization. In this paper, we investigate noninvasive approach to PH detection utilizing Magnetic Resonance Imaging ...
arxiv  

Reflex responses from the main pulmonary artery and bifurcation in anaesthetised dogs [PDF]

open access: yes, 2000
This study was undertaken to determine the reflex cardiovascular and respiratory responses to discrete stimulation of pulmonary arterial baroreceptors using a preparation in which secondary modulation of responses from other reflexes was prevented.
Drinkhill, M.J.   +3 more
core   +1 more source

Prognostic Value of Gamma-Glutamyltransferase in Male Patients With Idiopathic Pulmonary Arterial Hypertension

open access: yesFrontiers in Cardiovascular Medicine, 2020
Background: The elevated gamma-glutamyltransferase (GGT) activity is regarded as an indicator of cardiovascular disease, with males having higher values than females.
Gang-Hua Lu   +9 more
doaj   +1 more source

Efficient Uncertainty Quantification in a Multiscale Model of Pulmonary Arterial and Venous Hemodynamics [PDF]

open access: yesarXiv, 2023
Computational hemodynamics models are becoming increasingly useful in the management and prognosis of complex, multiscale pathologies, including those attributed to the development of pulmonary vascular disease. However, diseases like pulmonary hypertension are heterogeneous, and affect both the proximal arteries and veins as well as the ...
arxiv  

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