Results 71 to 80 of about 211,135 (314)

Reversal of pulmonary circulation

The Journal of Thoracic and Cardiovascular Surgery, 1975
The preliminary results and the technique of total reversal of the pulmonary circulation (RPC) are presented. Total RPC is technically feasible and not incompatible with life. It affords a new experimental model for in vivo study of pulmonary pathophysiology.
T J, Dosis, F, Thevoz, D L, Fisher, M H, Adatepe, P, Merkow, G J, Magovern   +5 more
openaire   +2 more sources

Advancing Clinical Trial Design in Pulmonary Hypertension [PDF]

, 2013
In pulmonary hypertension, as in many other diseases, there is a need for a smarter approach to evaluating new treatments. The traditional randomized controlled trial has served medical science well, but constrains the development of treatments for rare ...
D. Dunbar Ivy, Shen Xiao, Hsien Ming J. Hung, Xiao, Shen, Shien‐Chung Chow, Noreen R. Henig, Kawut, Steven M, Hung, Hsien Ming J, Grieve, Andy P, Stephen Dawe, Dawe, Stephen, Harnisch, Lutz O, Chow, Shien-Chung, Andy P. Grieve, Lutz O. Harnisch, Henig, Noreen R, Rahbar, Mohammad H, Steven M. Kawut, John Curram, Mohammad H. Rahbar, Curram, John, Ivy, D Dunbar, Wilkins, Martin R, Martin R. Wilkins   +23 more
core   +1 more source

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

Haemoptysis Caused by Right Intercostal Artery‐To‐Pulmonary Artery Fistulas Mimicking Cryptogenic Haemoptysis

Respirology Case Reports
Systemic artery‐to‐pulmonary artery fistulas (SA‐PAFs) are rare vascular anomalies, typically associated with chronic pulmonary or pleural inflammation. SA‐PAFs are categorised by their systemic arterial origin, arising either from the bronchial arteries
Kengo Sato, Masahiro Kawashima, Masaomi Maeda, Ibuki Kosai, Takafumi Kato, Keita Takeda, Hiroshi Igei, Kimihiko Masuda, Yoshiteru Morio, Hirotoshi Matsui   +9 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Early histological changes of pulmonary arterial hypertension disclosed by invasive cardiopulmonary exercise testing [PDF]

, 2019
Early diagnosis of pulmonary artery hypertension (PAH) is diagnostically challenging given the extent of pulmonary vascular remodeling required to bring about clinical signs and symptoms.
Price, Laura, Bhatti, Yousaf, Konstantinos Dimopoulos, Laura C. Price, Athol Wells, Wells, Athol, Kempny, Aleksander, Ranu, Harpreet, Rice, Alexandra J, S. John Wort, Colm McCabe, Aleksander Kempny, Dimopoulos, Konstantinos, Alexandra J. Rice, Wort, Stephen John, Harpreet Ranu, McCabe, Colm, Yousaf J. Bhatti   +17 more
core   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Electrocardiographic signs to differentiate between chronic thromboembolic pulmonary hypertension and intermediate-high risk acute pulmonary embolism

Scientific Reports
Acute pulmonary embolism (APE) and chronic thromboembolic pulmonary hypertension (CTEPH) both causedyspnoea and right ventricular (RV) overload, but require diff erent management.
Marcin Waligóra, Klaudia Zaczyńska, Jakub Stępniewski, Emilia Lis, Julia Hypnar, Wojciech Magoń, Kamil Jonas, Barbara Wziątek, Grzegorz Kopeć   +8 more
doaj   +1 more source

EXPRESS: Statement on imaging and pulmonary hypertension from the Pulmonary Vascular Research Institute (PVRI) [PDF]

, 2019
Pulmonary hypertension is highly heterogeneous and despite treatment advances it remains a life shortening condition. There have been significant advances in imaging technologies, but despite evidence of their potential clinical utility practice remains
Swift, Andrew J., van Beek, Edwin, Olschewski, H., Horst Olschewski, Kiely, D., Screaton, Nicholas J, Michal Schafer, Rahaghi, F., David G. Kiely, Rebecca Vandepool, Tawhai, M., Mazurek, Jeremy, Rahaghi, Farbod N., Vogel-Claussen, J., Swift, Andrew, Levin, David L., Tawhai, Merryn, Ivy, David D, Andrew J. Swift, Swift, A., Van Beek, Edwin Jr, Angela Lungu, Schiebler, Mark, Schiebler, M., Bwika, J., Jone, P.-N., Dunbar Ivy, Kawut, S.M., Peacock, Andrew J., Stephen J. Wort, Kiely, David, Levin, D., Wild, J., David L. Levin, Puri, G D, Wild, Jim M, Olschewski, Horst, Schafer, M., Vanderpool, R.R., Vonk-Noordegraaf, Anton, G.D. Puri, Wort, John, Peacock, A., Hassoun, Paul M, Hassoun, Paul, Hassoun, Paul M., Jone, Pei-Ni, Lungu, Angela, Vanderpool, Rebecca R, Moledina, S., Bwika, Jumaa, Schiebler, Mark L, Kiely, David G., Shahin Moledina, Farbod N. Rahaghi, Jim Lordan, Levin, David, Jens Vogel‐Claussen, Kawut, Steven M, Rahaghi, Farbod N, Wort, J., Ivy, D.D., Wild, Jim, Pei‐Ni Jone, Kawut, Steven M., Andrew J. Peacock, Puri, Goverdhan Dutt, Mazurek, J., Jumaa Bwika, Lordan, Jim, Zhao, Lan, Tawhi, Merryn, Dunbar, Ivy, Van Beek, E.J., Mazurek, Jeremy A, Screaton, Nicholas, Vonk-Noordegraaf, A., Rahaghi, Farbod, Steven M. Kawut, Zhao, L., Anton Vonk‐Noordegraaf, Wort, Stephen J., Vandepool, Rebecca, Ivy, Dunbar, Wort, S John, Lordan, J., Wild, Jim M., Moledina, Shahin, van Beek, Edwin J. R., Schafer, Michal, Kiely, David G, Paul M. Hassoun, Jim M. Wild, Swift, Andrew J, Puri, G. D., Vogel-Claussen, Jens, Jeremy A. Mazurek, Lungu, A., Puri, G.D., Screaton, N., Mazurek, Jeremy A., Nicholas Screaton, Merryn Tawhai, Hassoun, P., Mark Schiebler, Peacock, Andrew, Lan Zhao, Edwin J.R. van Beek   +107 more
core   +1 more source

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source