Results 81 to 90 of about 2,069,003 (398)

Advances in imaging for atrial fibrillation ablation. [PDF]

, 2011
Over the last fifteen years, our understanding of the pathophysiology of atrial fibrillation (AF) has paved the way for ablation to be utilized as an effective treatment option.
D'Silva, A, Wright, M
core   +2 more sources

Discovery of the pulmonary circulation [PDF]

European Heart Journal, 2016
A reply to a reply: From ancient Persia (before 637 AD) to William Harvey (17th Century AD)   We read with the great interest the response of Bestett and Couto1 to our last publication on the discovery of pulmonary circulation by ancient Persians.2 The authors claimed that the credit for the discovery of the pulmonary circulation should be given to ...
Hamed Arezaei, Arman Zargaran
openaire   +3 more sources

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Superoxide generated at mitochondrial complex III triggers acute responses to hypoxia in the pulmonary circulation.

American Journal of Respiratory and Critical Care Medicine, 2013
RATIONALE The role of reactive oxygen species (ROS) signaling in the O(2) sensing mechanism underlying acute hypoxic pulmonary vasoconstriction (HPV) has been controversial.
G. Waypa, J. Marks, R. Guzy, Paul T. Mungai, Jacqueline M. Schriewer, Danijela Dokic, M. Ball, P. Schumacker   +7 more
semanticscholar   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

A Multiscale Framework for Defining Homeostasis in Distal Vascular Trees: Applications to the Pulmonary Circulation [PDF]

arXiv, 2020
Coupling hemodynamics with vessel wall growth and remodeling (G&R) is crucial for understanding pathology at distal vasculature to study progression of incurable vascular diseases, such as pulmonary arterial hypertension. The present study is the first modeling attempt that focuses on defining homeostatic baseline values in distal pulmonary vascular ...
arxiv  

Computer simulation of surgical interventions for the treatment of refractory pulmonary hypertension [PDF]

arXiv, 2021
This paper describes computer models of three interventions used for treating refractory pulmonary hypertension (RPH). These procedures create either an atrial septal defect, a ventricular septal defect, or, in the case of a Potts shunt, a patent ductus arteriosus.
arxiv  

Acute pulmonary hypertension caused by tumor embolism: a report of two cases. [PDF]

, 2015
Acute pulmonary hypertension leading to right ventricular failure and circulatory collapse is usually caused by thromboembolic obstruction of the pulmonary circulation.
Liaudet, L., Mury, C., Nobile, A., Rotman, S., Schneider, A.G.   +4 more
core   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Monitoring and Control System Development and Experimental Validation for a Novel Extrapulmonary Respiratory Support Setup [PDF]

arXiv, 2021
This paper presents a novel mechatronic setup intended for providing respiratory support to patients suffering from pulmonary failure. The setup relies upon the circulation of an oxygenated perfluorocarbon (PFC) through the abdominal cavity. Such circulation provides a potential pathway for the transport of oxygen to the bloodstream.
arxiv