Results 101 to 110 of about 211,135 (314)

A case of left atrial myxoma accompanied by pancytopenia and pathological findings suggestive of pulmonary hypertension

, 1974
A case of left atrial myxoma accompanied by peculiar symptoms is reported. A 15-year old boy had progressive congestive heart failure and three episodes of acute attacks of panctyopenia. The anemia was accompanied by helmet-shaped, broken red blood cells,
Ogawa, Katsuo, Ofuji, Tadashi, Sato, Keiichiro, Kawanishi, Koichi   +3 more
core   +1 more source

Pulmonary vasoconstrictor action of KCNQ potassium channel blockers [PDF]

, 2006
KCNQ channels have been widely studied in the nervous system, heart and inner ear, where they have important physiological functions. Recent reports indicate that KCNQ channels may also be expressed in portal vein where they are suggested to influence ...
Joshi, Shreena, Gurney Alison M, Prabhu Balan, Alison M Gurney, Gurney, Alyson M.; id_orcid, Balan Prabhu, Shreena Joshi, Gurney, Alison M., Joshi Shreena, Balan, Prabhu   +9 more
core   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

Advanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang, Jiajia Liu, Jianguo Wen, Yangyang Luo, Zhiwei Fan, Liren Yang, Xi Hu, Ruihan Luo, Yankai Yu, Sophia Li, Weiling Zhao, Xiaobo Zhou   +11 more
wiley   +1 more source

Isolated right pulmonary artery discontinuity [PDF]

, 2000
Unilateral “absence” of the pulmonary artery is an uncommon malformation frequently associated with congenital heart disease. In fact, the pulmonary artery is typically discontinuous from the main pulmonary artery, not absent.
Vincent, J.A., Epstein, M.L., Turner, Daniel   +2 more
core  

Catheter ablation of atrial fibrillation : radiofrequency catheter ablation for redo procedures after cryoablation

, 2013
Aim: To evaluate the effectiveness of two different strategies using radiofrequency catheter ablation for redo procedures after cryoablation of atrial fibrillation. Methods: Thirty patients (paroxysmal atrial fibrillation: 22 patients, persistent atrial
Gramley, Felix, Kettering, Klaus
core   +1 more source

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

Advanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen, Zhentao Zhang, Lilian Sakai, Yanping Xu, Luxi Zhang, Han Ye, William Sollenberger, Takahide Ikeda, Zhiyu Yan, Keerthika Sathish, Usman Alizai, Haitao Wen, Timothy M. Pawlik, Heather L. Chandler, Hua Zhu   +14 more
wiley   +1 more source

Matrix metalloproteinase 7 in diagnosis and differentiation of pulmonary arterial hypertension [Elektronisk resurs]

, 2019
Pulmonary arterial hypertension is a severe disease for which diagnosis often is delayed. Matrix metalloproteinases have been suggested to play a role in vascular remodeling and pulmonary hypertension development. Our aim was therefore to investigate the
Bouzina, Habib,, Arvidsson, Mattias,, Ahmed, Abdulla,, Lund University., Rådegran, Göran,   +4 more
core   +1 more source

Plasma ADAMTS13 and von Willebrand factor in diagnosis and prediction of prognosis in pulmonary arterial hypertension [Elektronisk resurs]

, 2021
To improve outcome in pulmonary arterial hypertension, earlier diagnosis and better prognostic assessments are required. We aimed to investigate the diagnostic and prognostic potential of plasma proteins related to pathways recognized in pulmonary ...
Ahmed, Salaheldin,, Ahmed, Abdulla,, Lund University., Rådegran, Göran,   +3 more
core   +1 more source

SERS Facemask for Rapid and Portable Sensing Mycobacterium Tuberculosis Antigens for TB Screening

Advanced Science, EarlyView.
Our study introduced an Au─Ag embedded covalent organic framework (U@COF) ‐mediated facemask for sensing TB antigen ESAT‐6/CFP‐10 complex in clinical droplet samples toward TB screening. Practical analysis of clinical samples demonstrated the availability of our facemask, which is capable of identifying the TB subjects (N = 17) from healthy candidates (
Lingzhi Chen, Jiaqi Yu, Jing Xu, Lingqi Chen, Ninghao Zhang, Wenrui Li, Runmin Zeng, Xiaomin Luo, Yiqun Chang, Jiayin Lai, Wenshi Huang, Xiaochen Liang, Ting Zhao, Shanze Chen, Huaihong Cai, Yanguang Cong, Pinghua Sun, Jiang Pi, Xueqin Huang, Haibo Zhou, Junxia Zheng   +20 more
wiley   +1 more source

Functional impact of exercise pulmonary hypertension in patients with borderline resting pulmonary arterial pressure [PDF]

, 2017
Borderline resting mean pulmonary arterial pressure (mPAP) is associated with adverse outcomes and affects the exercise pulmonary vascular response. However, the pathophysiological mechanisms underlying exertional intolerance in borderline mPAP remain ...
Oliveira, Rudolf K. F., Rudolf K. F. Oliveira, Mario Santos, Systrom, David, Aaron B. Waxman, Waxman, Aaron B., Maron, Bradley A., Systrom, David M., Bradley A. Maron, Santos, Mario, Mariana Faria‐Urbina, Maron, Bradley, Faria-Urbina, Mariana, David M. Systrom, Oliveira, Rudolf K. F. [UNIFESP], Waxman, Aaron   +15 more
core   +1 more source