Results 91 to 100 of about 11,770,891 (406)

Early versus delayed pulmonary rehabilitation:A randomized controlled trial – Can we do it? [PDF]

, 2018
Providing outpatient pulmonary rehabilitation (PR) following hospitalization for an acute exacerbation of chronic obstructive pulmonary disease (AECOPD) has been found to improve exercise capacity, quality of life and a reduction in unplanned hospital ...
Revitt, Olivia, Sewell, Louise, Singh, Sally   +2 more
core   +1 more source

Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease [PDF]

, 2022
Yuan Zhan, Jinkun Chen, Jixing Wu, Yiya Gu, Qian Huang, Zhesong Deng, Shanshan Chen, Xiaojie Wu, Yongman Lv, Zhilin Zeng, Jungang Xie   +10 more
openalex   +1 more source

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19.

New England Journal of Medicine, 2020
BACKGROUND Progressive respiratory failure is the primary cause of death in the coronavirus disease 2019 (Covid-19) pandemic. Despite widespread interest in the pathophysiology of the disease, relatively little is known about the associated morphologic ...
M. Ackermann, S. Verleden, M. Kuehnel, A. Haverich, T. Welte, F. Laenger, A. Vanstapel, C. Werlein, Helge Stark, A. Tzankov, William Li, V. Li, S. Mentzer, D. Jonigk   +13 more
semanticscholar   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

The effect of adding inhaled corticosteroids to tiotropium and long-acting beta(2)-agonists for chronic obstructive pulmonary disease (Review) [PDF]

, 2011
BackgroundLong-acting bronchodilators comprising long-acting beta(2)-agonists and the anticholinergic agent tiotropiumare commonly used, either on their own or in combination, for managing persistent symptoms of chronic obstructive pulmonary disease ...
Aaron, Aaron, Agarwal, Akazawa, Appleton, Barr, Beeh, Berger, Briggs, Calverley, Dalal, Effing, Higgins, Hutchinson, Johnson, Kaplan, Lacasse, Meer, Najafzadeh, Najafzadeh, Nannini, Nannini Luis, Proskocil, Rodrigo, Rodrigo, Roisman, Singh, Singh, Tanaka, Tashkin, Wallukat, Welsh, Yang   +32 more
core   +1 more source

Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease.

New England Journal of Medicine, 2015
BACKGROUND Chronic obstructive pulmonary disease (COPD) is thought to result from an accelerated decline in forced expiratory volume in 1 second (FEV1) over time.
P. Lange, B. Celli, A. Agustí, Gorm Boje Jensen, M. Divo, R. Faner, S. Guerra, J. Marott, F. Martinez, P. Martínez-Camblor, P. Meek, C. Owen, H. Petersen, V. Pinto-Plata, P. Schnohr, A. Sood, J. Soriano, Y. Tesfaigzi, J. Vestbo   +18 more
semanticscholar   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Prediction of progressive pulmonary fibrosis in patients with anti-synthetase syndrome-associated interstitial lung disease [PDF]

, 2023
Hongyan Fu, Ziyao Zheng, Zhenping Zhang, Yanjuan Yang, Jieda Cui, Zhaojun Wang, Jing Xue, Shuhong Chi, Mengshu Cao, Juan Chen   +9 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Assessment of inflammatory markers, disease severity and comorbidities in very elderly patients with acute respiratory diseases

Archives of Medical Science, 2020
Introduction The study aimed to evaluate the potential role of inflammatory markers (neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), platelet to mean platelet volume (PLT/MPV), C-reactive protein (CRP), CRP/albumin) and ...
Armagan Hazar, Baran Gundogus
doaj   +1 more source