Deep learning automated quantification of lung disease in pulmonary hypertension on CT pulmonary angiography: A preliminary clinical study with external validation [PDF]
arXiv, 2023 Purpose: Lung disease assessment in precapillary pulmonary hypertension (PH) is essential for appropriate patient management. This study aims to develop an artificial intelligence (AI) deep learning model for lung texture classification in CT Pulmonary Angiography (CTPA), and evaluate its correlation with clinical assessment methods.
arxiv
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
A Trial of Home Oxygen for Acute Asthma Attacks for the Prevention of Asthmatic Death
Allergology International, 2005 Physicians are very much concerned that death from asthma has not significantly declined despite modern treatment. Since most asthma deaths take place at home it is mandatory to keep in mind that adequate management should be commenced as early as ...
Seishiro Miyagi +3 more
doaj +1 more source
Physical activity and its clinical correlates in chronic thromboembolic pulmonary hypertension
Pulmonary Circulation, 2022 Limited data are available on physical activity (PhA) levels in chronic thromboembolic pulmonary hypertension (CTEPH) patients, as well as on the clinical utility of PhA measurements using questionnaires and accelerometers.
Cristine Schmidt +6 more
doaj +1 more source
Hierarchical Classification of Pulmonary Lesions: A Large-Scale Radio-Pathomics Study [PDF]
, 2020 Diagnosis of pulmonary lesions from computed tomography (CT) is important but challenging for clinical decision making in lung cancer related diseases. Deep learning has achieved great success in computer aided diagnosis (CADx) area for lung cancer, whereas it suffers from label ambiguity due to the difficulty in the radiological diagnosis. Considering
arxiv +1 more source
New targets for resolution of airway remodeling in obstructive lung diseases. [PDF]
, 2018 Airway remodeling (AR) is a progressive pathological feature of the obstructive lung diseases, including asthma and chronic obstructive pulmonary disease (COPD).
Deshpande, Deepak A. +2 more
core +2 more sources
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Impact of Nosocomial COVID-19 Infection Among Hospitalized Patients with Respiratory Diseases
Bagcilar Medical Bulletin, 2023 Objective: There are very few studies concerning the frequency and course of nosocomial Coronavirus disease-2019 (COVID-19) infection among patients hospitalized having diseases other than COVID-19.
Mediha Gönenç Ortaköylü +6 more
doaj +1 more source
Attention based CNN-LSTM Network for Pulmonary Embolism Prediction on Chest Computed Tomography Pulmonary Angiograms [PDF]
arXiv, 2021 With more than 60,000 deaths annually in the United States, Pulmonary Embolism (PE) is among the most fatal cardiovascular diseases. It is caused by an artery blockage in the lung; confirming its presence is time-consuming and is prone to over-diagnosis.
arxiv
Anomalous right pulmonary artery from the aorta [PDF]
, 2006 Anomalous origin of the right pulmonary artery is a rare form of congenital heart disease. It usually presents in early infancy with heart failure and rapid development of pulmonary hypertension. There are about 131 cases reported in the literature and
Mokhtar, S.A.I. +2 more
core