Results 51 to 60 of about 10,951,042 (362)
Tracking dyspnea up to supplemental oxygen prescription among patients with pulmonary fibrosis
BMC Pulmonary Medicine, 2017 Background Dyspnea is the hallmark symptom of pulmonary fibrosis. Supplemental oxygen (O2) is prescribed to many patients with pulmonary fibrosis in hopes of alleviating dyspnea and improving physical functioning.
Amy L. Olson +10 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2022 Cor triatriatum sinister is a rare congenital anomaly characterized by the left-sided triatrial form of the heart. Diverse theories have been proposed regarding its formation, and the failure of incorporation of the common pulmonary vein into the left ...
I-Hsin Tai +14 more
doaj +1 more source
ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function
FEBS Letters, Volume 599, Issue 19, Page 2817-2827, October 2025.The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran +6 more
wiley +1 more source
Idiopathic pulmonary arterial hypertension and co-existing lung disease: is this a new phenotype?
Pulmonary Circulation, 2020 Patients classified as idiopathic pulmonary arterial hypertension (defined as Group 1 on European Respiratory Society (ERS)/European Cardiac Society (ESC) criteria) may have evidence of minor co-existing lung disease on thoracic computed tomography.
Andrew J. Peacock +16 more
doaj +1 more source
Storage conditions of high‐fat diets affect pulmonary inflammation
Physiological Reports, 2021 Obesity alters the risks and outcomes of inflammatory lung diseases. It is important to accurately recapitulate the obese state in animal models to understand these effects on the pathogenesis of disease.
Marta Kokoszynska +8 more
doaj +1 more source
Nature Genetics, 2018 Reduced lung function predicts mortality and is key to the diagnosis of chronic obstructive pulmonary disease (COPD). In a genome-wide association study in 400,102 individuals of European ancestry, we define 279 lung function signals, 139 of which are ...
N. Shrine +108 more
semanticscholar +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Non-tuberculous mycobacterial pulmonary disease
European Respiratory Journal, 2019 Nontuberculous mycobacterial pulmonary disease (NTM-PD) is a challenging infection which is becoming increasingly prevalent, particularly in the elderly, for reasons which are unknown.
S. Cowman +3 more
semanticscholar +1 more source
Pulmonary hydatid disease [PDF]
Thorax, 1972 Radiographic evidence is presented in confirmation of the contention that uncomplicated isolated pulmonary hydatid cysts are seldom completely circular and can be confidently recognized as hydatid cysts radiographically and fluoroscopically.
openaire +3 more sources