Results 11 to 20 of about 1,205,311 (368)

Clinical outcomes of radial probe endobronchial ultrasound using a guide sheath for diagnosis of peripheral lung lesions in patients with pulmonary emphysema

Respiratory Research, 2019
Background Generally, structural destruction of lung parenchyma, such as pulmonary emphysema, is considered to be related to the low diagnostic yields and high complication rates of lung biopsies of peripheral lung lesions.
Kyu Min Lee, Geewon Lee, Ahreum Kim, Jeongha Mok, Ji Won Lee, Yeon Joo Jeong, Eun-Jung Jo, Mi Hyun Kim, Kwangha Lee, Ki Uk Kim, Hye-Kyung Park, Min Ki Lee, Jung Seop Eom   +12 more
doaj   +2 more sources

Combined Pulmonary Fibrosis and Emphysema: Pulmonary Function Testing and a Pathophysiology Perspective

Medicina, 2019
Combined pulmonary fibrosis and emphysema (CPFE) has been increasingly recognized over the past 10−15 years as a clinical entity characterized by rather severe imaging and gas exchange abnormalities, but often only mild impairment in spirometric ...
Diana E. Amariei, Neal Dodia, Janaki Deepak, Stella E. Hines, Jeffrey R. Galvin, Sergei P. Atamas, Nevins W. Todd   +6 more
doaj   +2 more sources

A Low Peripheral Blood CD4/CD8 Ratio Is Associated with Pulmonary Emphysema in HIV. [PDF]

PLoS ONE, 2017
The prevalence of emphysema is higher among HIV-infected (HIV+) individuals compared to HIV-uninfected persons. While greater tobacco use contributes, HIV-related effects on immunity likely confer additional risk.
Matthew Triplette, Engi F Attia, Kathleen M Akgün, Guy W Soo Hoo, Matthew S Freiberg, Adeel A Butt, Cherry Wongtrakool, Matthew Bidwell Goetz, Sheldon T Brown, Christopher J Graber, Laurence Huang, Kristina Crothers   +11 more
doaj   +2 more sources

Predifferentiated amniotic fluid mesenchymal stem cells enhance lung alveolar epithelium regeneration and reverse elastase-induced pulmonary emphysema

Stem Cell Research & Therapy, 2019
Introduction Pulmonary emphysema is a major component of chronic obstructive pulmonary disease (COPD). Emphysema progression attributed not only to alveolar structure loss and pulmonary regeneration impairment, but also to excessive inflammatory response,
Ying-Wei Lan, Jing-Chan Yang, Chih-Ching Yen, Tsung-Teng Huang, Ying-Cheng Chen, Hsiao-Ling Chen, Kowit-Yu Chong, Chuan-Mu Chen   +7 more
doaj   +2 more sources

Distinct emphysema subtypes defined by quantitative CT analysis are associated with specific pulmonary matrix metalloproteinases. [PDF]

Respiratory Research, 2016
BACKGROUND: Emphysema is characterised by distinct pathological sub-types, but little is known about the divergent underlying aetiology. Matrix-metalloproteinases (MMPs) are proteolytic enzymes that can degrade the extracellular matrix and have been ...
Bourne, S, Coombs, NA, Elkington, PT, Estepar, RS, Harden, S, Kim, V, Ostridge, K, Staples, KJ, Washko, G, Wilkinson, TM, Williams, N   +10 more
core   +2 more sources

Cardiovascular Function in Pulmonary Emphysema [PDF]

BioMed Research International, 2013
Chronic obstructive pulmonary disease (COPD) and chronic cardiovascular disease, such as coronary artery disease, congestive heart failure, and cardiac arrhythmias, have a strong influence on each other, and systemic inflammation has been considered as the main linkage between them.
VISCA, Dina, AIELLO, Marina, CHETTA, Alfredo Antonio   +2 more
openaire   +5 more sources

Syndrome of Combined Pulmonary Fibrosis and Emphysema: An official research statement from American Thoracic Society (ATS), European Respiratory Society (ERS), Japanese Respiratory Society (JRS), and Asociación Latinoamericana de Tórax (ALAT)

American Journal of Respiratory and Critical Care Medicine, 2022
Background The presence of emphysema is relatively common in patients with fibrotic interstitial lung disease. This has been designated combined pulmonary fibrosis and emphysema (CPFE).
V. Cottin, M. Selman, Y. Inoue, A. Wong, T. Corte, K. Flaherty, M. Han, Joseph Jacob, K. Johannson, M. Kitaichi, Joyce S. Lee, A. Agustí, K. Antoniou, P. Bianchi, F. Caro, M. Florenzano, L. Galvin, T. Iwasawa, F. Martinez, R. Morgan, J. Myers, A. Nicholson, M. Occhipinti, V. Poletti, M. Salisbury, D. D. Sin, N. Sverzellati, T. Tonia, C. Valenzuela, C. Ryerson, A. Wells   +30 more
semanticscholar   +1 more source

Reversal of emphysema by restoration of pulmonary endothelial cells

Journal of Experimental Medicine, 2021
We tested the role of endothelial dysfunction in the development of COPD/emphysema. We found that restoration of lung endothelial cells and blockade of endothelial-derived leucine-rich α-2-glycoprotein perturbs the pathogenesis of COPD/emphysema.
S. Hisata, A. Racanelli, P. Kermani, Ryan Schreiner, S. Houghton, Brisa Palikuqi, Balvir Kunar, Aiyuan Zhou, K. McConn, Allyson Capili, D. Redmond, D. Nolan, Michael Ginsberg, B. Ding, F. Martinez, J. Scandura, S. Cloonan, S. Rafii, A. Choi   +18 more
semanticscholar   +1 more source

Pulmonary Rehabilitation in Emphysema [PDF]

Proceedings of the American Thoracic Society, 2008
Pulmonary rehabilitation is an established treatment for patients with chronic lung disease. Benefits include improvement in exercise tolerance, symptoms, and quality of life, with a reduction in the use of health care resources. As an adjunct to surgical programs, such as lung volume reduction surgery, pulmonary rehabilitation plays an important role ...
John J. Reilly, Barry J. Make, Andrew L. Ries   +2 more
openaire   +3 more sources

Automatic Emphysema Detection using Weakly Labeled HRCT Lung Images [PDF]

, 2018
A method for automatically quantifying emphysema regions using High-Resolution Computed Tomography (HRCT) scans of patients with chronic obstructive pulmonary disease (COPD) that does not require manually annotated scans for training is presented.
Carl, Jesper, Cheplygina, Veronika, de Bruijne, Marleen, Paschaloudi, Sofia, Peña, Isabel Pino, Vuust, Morten, Weinreich, Ulla Møller, Østergaard, Lasse Riis   +7 more
core   +7 more sources