Results 31 to 40 of about 72,126 (206)
Postgraduate Medicine, 1956 Patients with chronic pulmonary emphysema were analyzed on clinical and morphological standpoints. Pulmonary function tests and selective alveolobronchography were used for this study. Significant differences in two types of clinical features of chronic pulmonary emphysema were demonstrated on one aspect, and remarkable overlapping of alveolar and ...
B, HYDE, L, HYDE
openaire +6 more sources
Medicina, 2019 Combined pulmonary fibrosis and emphysema (CPFE) has been increasingly recognized over the past 10−15 years as a clinical entity characterized by rather severe imaging and gas exchange abnormalities, but often only mild impairment in spirometric ...
Diana E. Amariei +6 more
doaj +1 more source
Frontiers in Medicine, 2021 Objective: This study aimed to evaluate how emphysema extent and its regional distribution quantified by chest CT are associated with clinical and functional severity in patients with chronic obstructive pulmonary disease (COPD).Methods/Design: Patients ...
Plácido Gomes +15 more
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Advanced Science, EarlyView.Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu +12 more
wiley +1 more source
Three‐dimensional geometric morphometric analysis of diaphragmatic dome motion in COPD patients
The Anatomical Record, EarlyView.Abstract Diaphragmatic dysfunction is a hallmark of chronic obstructive pulmonary disease (COPD), especially in emphysema, where hyperinflation alters diaphragm geometry and impairs inspiratory mechanics. However, quantitative three‐dimensional (3D) assessments of diaphragmatic dome shape and motion across COPD phenotypes are limited.
José M. López‐Rey +5 more
wiley +1 more source
The impact of emphysema on surgical outcomes of early-stage lung cancer: a retrospective study
BMC Pulmonary Medicine, 2019 Background The presence of emphysema on computed tomography (CT) is associated with an increased frequency of lung cancer, but the postoperative outcomes of patients with pulmonary emphysema are not well known.
Seijiro Sato +6 more
doaj +1 more source
Impact of emphysema heterogeneity on pulmonary function. [PDF]
PLoS ONE, 2014 To investigate the association between emphysema heterogeneity in spatial distribution, pulmonary function and disease severity.We ascertained a dataset of anonymized Computed Tomography (CT) examinations acquired on 565 participants in a COPD study ...
Jieyang Ju +10 more
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Arthritis &Rheumatology, Accepted Article.Objective We evaluated baseline characteristics, treatment patterns, and outcomes in patients with systemic autoimmune rheumatic disease‐associated progressive pulmonary fibrosis (SARD‐PPF) and evaluated whether outcomes differed by SARD subtype. Methods The ILD‐PRO Registry is a prospective multicenter US registry of patients with PPF.
Sonali J Bracken +7 more
wiley +1 more source
Developmental Dynamics, EarlyView.Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane +4 more
wiley +1 more source
The Egyptian Journal of Radiology and Nuclear MedicineBackground Chronic obstructive pulmonary disease (COPD) has been a major public health problem. Although pulmonary function test remains the primary diagnostic method, quantitative computed tomography (QCT) analysis has become more significant in the ...
Taghreed Abdelaziz Nasr +4 more
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