Results 11 to 20 of about 72,126 (206)

Pulmonary interstitial emphysema in fatal asthma: case report and histopathological review

BMC Pulmonary Medicine, 2018
Background Mortality related to asthma has decreased worldwide since the introduction of inhaled corticosteroid therapy in the past decades. However, there are still some asthma fatalities identified mainly in populations with less access to regular ...
Thais Mauad, Felipe B. P. do Nascimento, Marisa Dolhnikoff, Milena C. M. Picka, Paulo H. N. Saldiva, on behalf of BIAS   +5 more
doaj   +1 more source

Pulmonary Comorbidities of Lung Emphysema

대한영상의학회지, 2018
Pulmonary emphysema is defined as the “abnormal permanent enlargement of the airspaces distal to the terminal bronchioles accompanied by destruction of the alveolar wall and without obvious fibrosis.” Pulmonary emphysema could result in various ...
Hye Rim Park, Young Tong Kim, Sung Shick Jou, Chan Ho Park   +3 more
doaj   +1 more source

The effect of PPE-induced emphysema and chronic LPS-induced pulmonary inflammation on atherosclerosis development in APOE*3-LEIDEN mice. [PDF]

PLoS ONE, 2013
BackgroundChronic obstructive pulmonary disease (COPD) is characterized by pulmonary inflammation, airways obstruction and emphysema, and is a risk factor for cardiovascular disease (CVD).
P Padmini S J Khedoe, Man C Wong, Gerry T M Wagenaar, Jaap J Plomp, Miranda van Eck, Louis M Havekes, Patrick C N Rensen, Pieter S Hiemstra, Jimmy F P Berbée   +8 more
doaj   +1 more source

Imaging Diagnosis of Interstitial Pneumonia with Emphysema (Combined Pulmonary Fibrosis and Emphysema)

Pulmonary Medicine, 2012
Based on clinical and radiological findings, Cottin defined combined pulmonary fibrosis and emphysema (CPFE) as pulmonary emphysema in the upper lungs and interstitial pneumonia in the lower lungs with various radiological patterns.
Fumikazu Sakai, Junya Tominaga, Akiko Kaga, Yutaka Usui, Minoru Kanazawa, Takashi Ogura, Noriyo Yanagawa, Tamiko Takemura   +7 more
doaj   +1 more source

In Vivo Electroporation-Mediated, Intrahepatic Alpha1 Antitrypsin Gene Transfer Reduces Pulmonary Emphysema in Pallid Mice

Pharmaceutics, 2020
Rationale: Mutation in the alpha1 antitrypsin (AAT) gene leads to low circulating levels of AAT, which is associated with several disease processes including pulmonary emphysema. The standard of care relies on substitution with plasma-purified AAT.
Marco A. Sutter, Tiziana P. Cremona, Izabela Nita, Eleonora Cavarra, Giuseppe Lungarella, Eli C. Lewis, Johannes C. Schittny, Thomas Geiser, Amiq Gazdhar   +8 more
doaj   +1 more source

Improvement of pulmonary arterial compliance by pulmonary vasodilator in pulmonary hypertension from combined pulmonary fibrosis and emphysema

Respiratory Medicine Case Reports, 2019
Combined pulmonary fibrosis and emphysema (CPFE) is a common but under-recognized syndrome characterized with distinct profiles of both pulmonary fibrosis and emphysema.
Kei Kusaka, Yoshiteru Morio, Yuya Kimura, Keita Takeda, Masahiro Kawashima, Kimihiko Masuda, Hirotoshi Matsui   +6 more
doaj   +1 more source

Differential regulation of muscle protein turnover in response to emphysema and acute pulmonary inflammation

Respiratory Research, 2017
Background Exacerbations in COPD are often accompanied by pulmonary and systemic inflammation, and associated with increased susceptibility to and prevalence of weight loss and muscle wasting.
Judith J. M. Ceelen, Annemie M. W. J. Schols, Stefan J. van Hoof, Chiel C. de Theije, Frank Verhaegen, Ramon C. J. Langen   +5 more
doaj   +1 more source

Carboxymethyl Chitosan Modified Oxymatrine Liposomes for the Alleviation of Emphysema in Mice via Pulmonary Administration

Molecules, 2022
Pulmonary emphysema is a fatal lung disease caused by the progressive thinning, enlargement and destruction of alveoli that is closely related to inflammation and oxidative stress.
Jianqing Peng, Zimin Cai, Qin Wang, Jia Zhou, Jinzhuan Xu, Di Pan, Tingting Chen, Guangqiong Zhang, Ling Tao, Yi Chen, Xiangchun Shen   +10 more
doaj   +1 more source

Genetic polymorphism in matrix metalloproteinase-9 and transforming growth factor-β1 and susceptibility to combined pulmonary fibrosis and emphysema in a Chinese population

Kaohsiung Journal of Medical Sciences, 2017
In this study, we aimed to explore the association of genetic polymorphism in matrix metalloproteinase-9 (MMP-9) and transforming growth factor-β1 (TGF-β1) and the susceptibility to combined pulmonary fibrosis and emphysema (CPFE).
Ling Xu, Wei Bian, Xiao-Hua Gu, Ce Shen
doaj   +1 more source

Effect of combined pulmonary fibrosis and emphysema on patients with connective tissue diseases and systemic sclerosis: a systematic review and meta-analysis

Arthritis Research & Therapy, 2021
Background This study aimed to analyze the literature systematically to determine the clinical characteristics and prognosis of patients with connective tissue disease (CTD) with combined pulmonary fibrosis and emphysema (CPFE) compared to those of ...
Bon San Koo, Kyu Yong Park, Hyun Jung Lee, Hyun Jung Kim, Hyeong Sik Ahn, Shin-Young Yim, Jae-Bum Jun   +6 more
doaj   +1 more source