Results 51 to 60 of about 1,251,660 (305)

Pulmonary Barotrauma Including Huge Pulmonary Interstitial Emphysema in an Adult with Status Asthmaticus: Diagnostic and Therapeutic Challenges

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2018
Introduction: Pulmonary interstitial emphysema is a rare finding defined as abnormal air collection inside the lung interstitial tissues. Described more frequently in ventilated new-borns, pulmonary interstitial emphysema is an uncommon barotrauma ...
Ahmed Khedher   +5 more
doaj   +1 more source

Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease [PDF]

open access: yes, 2011
Chronic obstructive pulmonary disease (COPD) is a global health problem. The current therapies for COPD are poorly effective and the mainstays of pharmacotherapy are bronchodilators.
Hongwei Yao   +3 more
core   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu   +4 more
wiley   +1 more source

Association between Image Characteristics on Chest CT and Severe Pleural Adhesion during Lung Cancer Surgery. [PDF]

open access: yesPLoS ONE, 2016
The aim of this study was to investigate the association between image characteristics on preoperative chest CT and severe pleural adhesion during surgery in lung cancer patients.
Kwang Nam Jin   +6 more
doaj   +1 more source

Pulmonary Emphysema Regional Distribution and Extent Assessed by Chest Computed Tomography Is Associated With Pulmonary Function Impairment in Patients With COPD

open access: yesFrontiers in Medicine, 2021
Objective: This study aimed to evaluate how emphysema extent and its regional distribution quantified by chest CT are associated with clinical and functional severity in patients with chronic obstructive pulmonary disease (COPD).Methods/Design: Patients ...
Plácido Gomes   +15 more
doaj   +1 more source

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

open access: yesAdvanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei   +11 more
wiley   +1 more source

Chronic Pulmonary Emphysema

open access: yesPostgraduate Medicine, 1956
Patients with chronic pulmonary emphysema were analyzed on clinical and morphological standpoints. Pulmonary function tests and selective alveolobronchography were used for this study. Significant differences in two types of clinical features of chronic pulmonary emphysema were demonstrated on one aspect, and remarkable overlapping of alveolar and ...
B, HYDE, L, HYDE
openaire   +6 more sources

Three‐dimensional geometric morphometric analysis of diaphragmatic dome motion in COPD patients

open access: yesThe Anatomical Record, EarlyView.
Abstract Diaphragmatic dysfunction is a hallmark of chronic obstructive pulmonary disease (COPD), especially in emphysema, where hyperinflation alters diaphragm geometry and impairs inspiratory mechanics. However, quantitative three‐dimensional (3D) assessments of diaphragmatic dome shape and motion across COPD phenotypes are limited.
José M. López‐Rey   +5 more
wiley   +1 more source

n-3系脂肪散を強化した食事療法が有効と考えられた肺気腫の一例

open access: yes, 1998
An effective treatment for the advanced stages of chronic obstructive pulmonary disease (COPD) has not been established yet. We report our recent experience of one patient with pulmonary emphysema treated by dietary supplementation of n-3 fatty acid for ...
Hosaki, Yasuhiro   +7 more
core   +1 more source

The impact of emphysema on surgical outcomes of early-stage lung cancer: a retrospective study

open access: yesBMC Pulmonary Medicine, 2019
Background The presence of emphysema on computed tomography (CT) is associated with an increased frequency of lung cancer, but the postoperative outcomes of patients with pulmonary emphysema are not well known.
Seijiro Sato   +6 more
doaj   +1 more source

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