Results 71 to 80 of about 72,126 (206)

Quantitative severity of pulmonary emphysema as a prognostic factor for recurrence in patients with surgically resected non‐small cell lung cancer

open access: yesThoracic Cancer, 2019
Background Pulmonary emphysema is a major component of chronic obstructive pulmonary disease and lung cancer. However the prognostic significance of quantitative emphysema severity in patients with lung cancer is unclear.
Seung Jun Lee   +13 more
doaj   +1 more source

Cost‐Effectiveness Analysis of Surgical Treatment of Varus Knee Osteoarthritis for Middle‐Aged Patients: A Multicenter Retrospective Cohort Study With Over 10‐Year Follow‐Up

open access: yesOrthopaedic Surgery, EarlyView.
In a multicenter retrospective cohort study with over 10 years of follow‐up, middle‐aged (45–65) varus knee osteoarthritis patients had equivalent clinical outcomes after open‐wedge high tibial osteotomy (OWHTO) or total knee arthroplasty (TKA). However, OWHTO was substantially more cost‐effective than TKA.
Runhua Zhou   +7 more
wiley   +1 more source

Association of Nasal and Inhalant Corticosteroids With Pediatric Perioral Dermatitis: A TriNetX Retrospective Cohort Study

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Although topical corticosteroids are known triggers in the development of perioral dermatitis (PD), investigation into inhalant and nasal corticosteroid preparations, commonly used to manage allergic rhinitis and asthma, remains limited to case series.
Taylor Merkle   +4 more
wiley   +1 more source

Phase I clinical trial of cell therapy in patients with advanced chronic obstructive pulmonary disease: follow-up of up to 3 years

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2013
BACKGROUND Chronic obstructive pulmonary disease is a major inflammatory disease of the airways and an enormous therapeutic challenge. Within the spectrum of chronic obstructive pulmonary disease, pulmonary emphysema is characterized by the destruction ...
Talita Stessuk   +5 more
doaj   +1 more source

Confined spaces in space: Cerebral implications of chronic elevations of inspired carbon dioxide and implications for long‐duration space travel

open access: yesExperimental Physiology, EarlyView.
Abstract Cerebrovascular regulation is critically dependent upon the arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_{\mathrm{2}}}}}$), owing to its effect on cerebral blood flow, tissue PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_{\mathrm{2}}}}}$, tissue proton concentration, cerebral metabolism and cognitive and neuronal ...
Jay M. J. R. Carr   +2 more
wiley   +1 more source

Predicting clinical outcome with phenotypic clusters using quantitative CT fibrosis and emphysema features in patients with idiopathic pulmonary fibrosis.

open access: yesPLoS ONE, 2019
BackgroundThe clinical course of IPF varies. This study sought to identify phenotyping with quantitative computed tomography (CT) fibrosis and emphysema features using a cluster analysis and to assess prognostic impact among identified clusters in ...
So Hyeon Bak   +6 more
doaj   +1 more source

Ventilation Imaging of the Lung at 0.55T With Continuous Slice Cycling

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 3, Page 1235-1244, September 2026.
ABSTRACT Purpose To propose and evaluate a novel method for pulmonary ventilation imaging, offering considerably improved SNR. Methods A continuous slice cycling (CSC) acquisition scheme is proposed to exclusively capture signal modulations from respiratory motion with increased SNR.
Andrea Leuthard   +4 more
wiley   +1 more source

Predifferentiated amniotic fluid mesenchymal stem cells enhance lung alveolar epithelium regeneration and reverse elastase-induced pulmonary emphysema

open access: yesStem Cell Research & Therapy, 2019
Introduction Pulmonary emphysema is a major component of chronic obstructive pulmonary disease (COPD). Emphysema progression attributed not only to alveolar structure loss and pulmonary regeneration impairment, but also to excessive inflammatory response,
Ying-Wei Lan   +7 more
doaj   +1 more source

TRPA1 Regulates Fibrosis‐Associated Transcriptional Pathways in Human Lung Epithelial Cells

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
ABSTRACT Transient receptor potential ankyrin 1 (TRPA1) is a cation channel originally identified in lung fibroblasts and extensively studied in sensory neurons, where it is associated with pain and neurogenic inflammation. We and others have recently shown that TRPA1 is also expressed in lung epithelial cells and that its expression is regulated by ...
Leevi Halonen   +5 more
wiley   +1 more source

Hamman's crunch—A pathognomonic sign of pneumomediastinum

open access: yesEquine Veterinary Education, Volume 38, Issue 9, Page e571-e576, September 2026.
Summary Pneumomediastinum, particularly spontaneous pneumomediastinum, is uncommon and presents a diagnostic challenge. In human medicine, auscultation of Hamman's crunch, a crepitant, crunching noise, audible over the cardiac region in synchrony with the heartbeat, is considered pathognomonic for pneumomediastinum.
S. McCullagh   +4 more
wiley   +1 more source

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