Results 61 to 70 of about 1,251,660 (305)

Ocrelizumab‐induced colitis: VigiBase disproportionality analysis, case reports and literature review

British Journal of Clinical Pharmacology, EarlyView.
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse, Christophe Hommel, Nadine Petitpain, Philippe Kerschen   +3 more
wiley   +1 more source

Management and prevention of chronic obstructive pulmonary disease exacerbations: a state of the art review [PDF]

, 2009
Exacerbations of chronic obstructive pulmonary disease (COPD) are important events in the natural history of this prevalent and devastating condition. This review provides a concise, state of the art summary on prevention and management of exacerbations.
Hurst, JR, Hurst John R, Wedzicha Jadwiga A, Wedzicha, JA, John R Hurst, Jadwiga A Wedzicha   +5 more
core   +1 more source

Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants

Developmental Dynamics, EarlyView.
Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane, Angelina Almiroudis, Kaitlyn E. Donnelly, Robert S. Haltiwanger, Bernadette C. Holdener   +4 more
wiley   +1 more source

Severe chest and back pain due to extra-pulmonary emphysema above 5,000 m: a series of case reports

Frontiers in Medicine
BackgroundExtra-pulmonary emphysema is characterized by the presence of gas within loose soft tissues outside the lungs. This condition is frequently mistaken for acute cardiovascular diseases, leading to potential misdiagnosis.
Zhixin Gan, Jialin Wu, Jingdu Tian, Xiaoli Han, Qian Yang, Lei Zhang, Xi Yang, Xiaobo Han   +7 more
doaj   +1 more source

Impact of emphysema heterogeneity on pulmonary function. [PDF]

PLoS ONE, 2014
To investigate the association between emphysema heterogeneity in spatial distribution, pulmonary function and disease severity.We ascertained a dataset of anonymized Computed Tomography (CT) examinations acquired on 565 participants in a COPD study ...
Jieyang Ju, Ruosha Li, Suicheng Gu, Joseph K Leader, Xiaohua Wang, Yahong Chen, Bin Zheng, Shandong Wu, David Gur, Frank Sciurba, Jiantao Pu   +10 more
doaj   +1 more source

Robotic‐Assisted Extended Sistrunk Approach (RESA) for Salvage Surgery After Head and Neck Irradiation

Head &Neck, EarlyView.
ABSTRACT Background The robotic‐assisted extended “Sistrunk” approach (RESA) is a minimally invasive technique providing access to hypopharyngeal and laryngeal structures via a submental incision and vallecular pharyngotomy, bypassing the base of tongue.
Bartosz Wojtera, Avinash Beharry, Karma Lambercy, Pascaline Dübi, Jelena Todic, Christian Simon   +5 more
wiley   +1 more source

Airway and emphysema assessment by quantitative CT among emphysema phenotype of chronic obstructive pulmonary disease

The Egyptian Journal of Radiology and Nuclear Medicine
Background Chronic obstructive pulmonary disease (COPD) has been a major public health problem. Although pulmonary function test remains the primary diagnostic method, quantitative computed tomography (QCT) analysis has become more significant in the ...
Taghreed Abdelaziz Nasr, Hosny Abdelghany, Nasr M. Osman, Azza Farag Said, Mohamed Ahmed Abdelsamie   +4 more
doaj   +1 more source

Pulmonary interstitial emphysema presenting in a woman on the intensive care unit: case report and review of literature

Journal of Medical Case Reports, 2011
Introduction Pulmonary interstitial emphysema is a life-threatening form of ventilator-induced lung injury. We present one of the few reported adult cases of pulmonary interstitial emphysema in a woman with respiratory failure admitted to our intensive ...
Jovaisa Tomas, Sherren Peter B
doaj   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

A formula for predicting emphysema extent in combined idiopathic pulmonary fibrosis and emphysema

Respiratory Research
Background No single pulmonary function test captures the functional effect of emphysema in idiopathic pulmonary fibrosis (IPF). Without experienced radiologists, other methods are needed to determine emphysema extent. Here, we report the development and
Athol U. Wells, Joseph Jacob, Nicola Sverzellati, Gary Cross, Joseph Barnett, Angelo De Lauretis, Katerina Antoniou, Derek Weycker, Mark Atwood, Klaus-Uwe Kirchgaessler, Vincent Cottin   +10 more
doaj   +1 more source