Results 1 to 10 of about 1,492,506 (291)

Genome-wide DNA methylation dynamics in carbon tetrachloride-induced mice liver fibrosis [PDF]

Iranian Journal of Basic Medical Sciences, 2023
Objective(s): Many persistent harmful stimuli can result in chronic liver diseases, which lead to about 2 million deaths per year in the whole world. Liver fibrosis was found to exist in all kinds of chronic liver diseases.
Deming Li, Xiaoshu Guo, Wenyu Zhao, Jingyu Chen, Cong Xia, Guoying Yu   +5 more
doaj   +1 more source

Nos2 deficiency enhances carbon tetrachloride-induced liver injury in aged mice [PDF]

Iranian Journal of Basic Medical Sciences, 2020
Objective(s): As a multifunctional molecule, NO has different effects on liver injury. The present work aimed to investigate the effects of Nos2 knockout (KO) on acute liver injury in aged mice treated with carbon tetrachloride (CCl4).
Deming Li, Yaping Song, Yahao Wang, Yuedong Guo, Zhaoke Zhang, Ganggang Yang, Gaiping Wang, Cunshuan Xu   +7 more
doaj   +1 more source

Evaluation of Pulmonary Fibrosis Outcomes by Race and Ethnicity in US Adults [PDF]

, 2023
Importance: Pulmonary fibrosis (PF) is characterized by progressive scarring of lung tissue and poor survival. Racial and ethnic minority populations face the greatest risk of morbidity and mortality from disparities impacting respiratory health, but the
Adegunsoye, Ayodeji, Chung, Jonathan, Flaherty, Kevin R., Freiheit, Elizabeth, Garcia, Christine Kim, Garcia, Nicole, Ghodrati, Sahand, Jablonski, Renea, Kaul, Bhavika, Lee, Cathryn T., Newton, Chad A., Oldham, Justin M., Strek, Mary E., Vij, Rekha, White, Emily N., Wolters, Paul J   +15 more
core   +1 more source

Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults: An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline

American Journal of Respiratory and Critical Care Medicine, 2022
Background This American Thoracic Society, European Respiratory Society, Japanese Respiratory Society, and Asociación Latinoamericana de Tórax guideline updates prior idiopathic pulmonary fibrosis (IPF) guidelines and addresses the progression of ...
G. Raghu, M. Rémy-Jardin, L. Richeldi, C. Thomson, Y. Inoue, T. Johkoh, M. Kreuter, D. Lynch, T. Maher, F. Martinez, M. Molina-Molina, J. Myers, A. Nicholson, C. Ryerson, M. Strek, L. Troy, M. Wijsenbeek, M. Mammen, Tanzib Hossain, B. Bissell, D. Herman, S. Hon, F. Kheir, Y. H. Khor, M. Macrea, K. Antoniou, Demosthenes Bouros, I. Buendía-Roldán, F. Caro, B. Crestani, L. Ho, J. Morisset, A. Olson, A. Podolanczuk, V. Poletti, M. Selman, Thomas J. Ewing, S. Jones, S. Knight, M. Ghazipura, K. Wilson   +40 more
semanticscholar   +1 more source

Establishing CREATE: lessons learned in setting up a training environment for early-career researchers in respiratory medicine

BMC Medical Education, 2022
Background The purpose of the National Health and Medical Research Council Centre of Research Excellence in Pulmonary Fibrosis (CRE-PF) is to improve and extend the lives of patients living with pulmonary fibrosis through the development of a ...
Katherine Christian, Alison Hey-Cunningham, Tamera Corte, Nicole Goh, Jade Jaffar, Paul Reynolds, Alan Teoh, Lauren Troy   +7 more
doaj   +1 more source

Idiopathic Pulmonary Fibrosis: An Update on Pathogenesis

Frontiers in Pharmacology, 2022
Idiopathic pulmonary fibrosis (IPF) is a progressive, lethal fibrotic lung disease that occurs primarily in middle-aged and elderly adults. It is a major cause of morbidity and mortality. With an increase in life expectancy, the economic burden of IPF is
Qian Mei, Zhe Liu, He-Ning Zuo, Zhenhua Yang, Jing Qu   +4 more
semanticscholar   +1 more source

Pulmonary Fibrosis in Children [PDF]

Journal of Clinical Medicine, 2019
Pulmonary fibrosis (PF) is a very rare condition in children, which may be observed in specific forms of interstitial lung disease. None of the clinical, radiological, or histological descriptions used for PF diagnosis in adult patients, especially in situations of idiopathic PF, can apply to pediatric situations.
Nadia Nathan, Chiara Sileo, Guillaume Thouvenin, Laura Berdah, Céline Delestrain, Effrosyne Manali, Spyros Papiris, Pierre-Louis Léger, Hubert Ducou le Pointe, Aurore Coulomb l’Hermine, Annick Clement   +10 more
openaire   +5 more sources

Artificial neural network identified the significant genes to distinguish Idiopathic pulmonary fibrosis

Scientific Reports, 2023
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease that causes irreversible damage to lung tissue characterized by excessive deposition of extracellular matrix (ECM) and remodeling of lung parenchyma.
Zhongzheng Li, Shenghui Wang, Huabin Zhao, Peishuo Yan, Hongmei Yuan, Mengxia Zhao, Ruyan Wan, Guoying Yu, Lan Wang   +8 more
doaj   +1 more source

Pulmonary Fibrosis as a Result of Acute Lung Inflammation: Molecular Mechanisms, Relevant In Vivo Models, Prognostic and Therapeutic Approaches

International Journal of Molecular Sciences, 2022
Pulmonary fibrosis is a chronic progressive lung disease that steadily leads to lung architecture disruption and respiratory failure. The development of pulmonary fibrosis is mostly the result of previous acute lung inflammation, caused by a wide variety
I. Savin, M. Zenkova, A. Sen’kova
semanticscholar   +1 more source

Endothelial cell-derived MMP19 promotes pulmonary fibrosis by inducing E(nd)MT and monocyte infiltration

Cell Communication and Signaling, 2023
Background Matrix metalloproteinases (MMPs) play important roles in remodeling the extracellular matrix and in the pathogenesis of idiopathic pulmonary fibrosis (IPF).
Weiming Zhao, Lan Wang, Juntang Yang, Xinyu Chen, Xiaoshu Guo, Kai Xu, Ningdan Wang, Wenyu Zhao, Cong Xia, Hui Lian, Ivan Rosas, Guoying Yu   +11 more
doaj   +1 more source