Results 11 to 20 of about 412,177 (358)
GSR Deficiency Exacerbates Oxidative Stress and Promotes Pulmonary Fibrosis [PDF]
BiomoleculesIdiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disorder characterized by excessive scarring of lung tissue, predominantly affecting middle-aged and elderly populations.
Wenyu Zhao +10 more
doaj +2 more sources
Genome-wide DNA methylation dynamics in carbon tetrachloride-induced mice liver fibrosis [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): Many persistent harmful stimuli can result in chronic liver diseases, which lead to about 2 million deaths per year in the whole world. Liver fibrosis was found to exist in all kinds of chronic liver diseases.
Deming Li +5 more
doaj +1 more source
Nos2 deficiency enhances carbon tetrachloride-induced liver injury in aged mice [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): As a multifunctional molecule, NO has different effects on liver injury. The present work aimed to investigate the effects of Nos2 knockout (KO) on acute liver injury in aged mice treated with carbon tetrachloride (CCl4).
Deming Li +7 more
doaj +1 more source
BMC Medical Education, 2022 Background The purpose of the National Health and Medical Research Council Centre of Research Excellence in Pulmonary Fibrosis (CRE-PF) is to improve and extend the lives of patients living with pulmonary fibrosis through the development of a ...
Katherine Christian +7 more
doaj +1 more source
Scientific Reports, 2023 Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease that causes irreversible damage to lung tissue characterized by excessive deposition of extracellular matrix (ECM) and remodeling of lung parenchyma.
Zhongzheng Li +8 more
doaj +1 more source
Cell Communication and Signaling, 2023 Background Matrix metalloproteinases (MMPs) play important roles in remodeling the extracellular matrix and in the pathogenesis of idiopathic pulmonary fibrosis (IPF).
Weiming Zhao +11 more
doaj +1 more source
Idiopathic pulmonary fibrosis [PDF]
Orphanet Journal of Rare Diseases, 2008 Idiopathic pulmonary fibrosis (IPF) is a non-neoplastic pulmonary disease that is characterized by the formation of scar tissue within the lungs in the absence of any known provocation. IPF is a rare disease which affects approximately 5 million persons worldwide.
Paul W. Noble, Eric B. Meltzer
openaire +4 more sources
Cell Death Discovery, 2023 Idiopathic pulmonary fibrosis is a progressive and fatal interstitial lung disease with a poor prognosis and limited therapeutic options, which is characterized by aberrant myofibroblast activation and pathological remodeling of the extracellular matrix,
Ruyan Wan +10 more
doaj +1 more source
Fat storage-inducing transmembrane proteins: beyond mediating lipid droplet formation
Cellular & Molecular Biology Letters, 2022 Fat storage-inducing transmembrane proteins (FITMs) were initially identified in 2007 as members of a conserved endoplasmic reticulum (ER) resident transmembrane protein gene family, and were found to be involved in lipid droplet (LD) formation. Recently,
Gaiping Wang +5 more
doaj +1 more source
, 2005 Idiopathic pulmonary fibrosis (IPF) is a chronic fibrosing lung disease limited to the lungs and associated with the histologic appearance of usual interstitial pneumonia (UIP) on surgical lung biopsy. The estimated prevalence in the United States is between 35,000 and 55,000 cases,and evidence suggests that the prevalence is increasing for IPF.
Zisman, David A. +4 more
openaire +2 more sources