Results 11 to 20 of about 1,854,852 (401)

Post-COVID-19 pulmonary fibrosis: An ongoing concern

open access: yesAnnals of Thoracic Medicine, 2023
Coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 rapidly spread across the globe causing over 6 million deaths and major compromization of health facilities.
Nuha Alrajhi
semanticscholar   +1 more source

Artificial neural network identified the significant genes to distinguish Idiopathic pulmonary fibrosis

open access: yesScientific Reports, 2023
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease that causes irreversible damage to lung tissue characterized by excessive deposition of extracellular matrix (ECM) and remodeling of lung parenchyma.
Zhongzheng Li   +8 more
doaj   +1 more source

Idiopathic pulmonary fibrosis

open access: yesLa Presse Médicale, 2023
Idiopathic pulmonary fibrosis (IPF) is a progressive devastating lung disease with substantial morbidity. It is associated with cough, dyspnea and impaired quality of life. If left untreated, IPF has a median survival of 3 years. IPF affects ∼3 million people worldwide, with increasing incidence in older patients. The current concept of pathogenesis is
Thomas Koudstaal, Marlies S. Wijsenbeek
openaire   +2 more sources

Progressive pulmonary fibrosis: an expert group consensus statement

open access: yesEuropean Respiratory Journal, 2022
This expert group consensus statement emphasises the need for standardising the definition of progressive fibrosing interstitial lung diseases (F-ILDs), with an accurate initial diagnosis being of paramount importance in ensuring appropriate initial ...
S. Rajan   +21 more
semanticscholar   +1 more source

Pulmonary Fibrosis as a Result of Acute Lung Inflammation: Molecular Mechanisms, Relevant In Vivo Models, Prognostic and Therapeutic Approaches

open access: yesInternational Journal of Molecular Sciences, 2022
Pulmonary fibrosis is a chronic progressive lung disease that steadily leads to lung architecture disruption and respiratory failure. The development of pulmonary fibrosis is mostly the result of previous acute lung inflammation, caused by a wide variety
I. Savin, M. Zenkova, A. Sen’kova
semanticscholar   +1 more source

Endothelial cell-derived MMP19 promotes pulmonary fibrosis by inducing E(nd)MT and monocyte infiltration

open access: yesCell Communication and Signaling, 2023
Background Matrix metalloproteinases (MMPs) play important roles in remodeling the extracellular matrix and in the pathogenesis of idiopathic pulmonary fibrosis (IPF).
Weiming Zhao   +11 more
doaj   +1 more source

Idiopathic pulmonary fibrosis [PDF]

open access: yesOrphanet Journal of Rare Diseases, 2008
Idiopathic pulmonary fibrosis (IPF) is a non-neoplastic pulmonary disease that is characterized by the formation of scar tissue within the lungs in the absence of any known provocation. IPF is a rare disease which affects approximately 5 million persons worldwide.
Noble Paul W, Meltzer Eric B
openaire   +3 more sources

Targeting Oxidative Stress as a Therapeutic Approach for Idiopathic Pulmonary Fibrosis

open access: yesFrontiers in Pharmacology, 2022
Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease characterized by an abnormal reepithelialisation, an excessive tissue remodelling and a progressive fibrosis within the alveolar wall that are not due to infection or cancer ...
C. Estornut   +4 more
semanticscholar   +1 more source

ADRB2 inhibition combined with antioxidant treatment alleviates lung fibrosis by attenuating TGFβ/SMAD signaling in lung fibroblasts

open access: yesCell Death Discovery, 2023
Idiopathic pulmonary fibrosis is a progressive and fatal interstitial lung disease with a poor prognosis and limited therapeutic options, which is characterized by aberrant myofibroblast activation and pathological remodeling of the extracellular matrix,
Ruyan Wan   +10 more
doaj   +1 more source

Immune dysregulation as a driver of idiopathic pulmonary fibrosis.

open access: yesJournal of Clinical Investigation, 2021
Idiopathic pulmonary fibrosis (IPF) affects hundreds of thousands of people worldwide, reducing their quality of life and leading to death from respiratory failure within years of diagnosis.
K. Shenderov   +3 more
semanticscholar   +1 more source

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