Results 11 to 20 of about 1,731,614 (343)

Evaluation of Pulmonary Fibrosis Outcomes by Race and Ethnicity in US Adults [PDF]

open access: yes, 2023
Importance: Pulmonary fibrosis (PF) is characterized by progressive scarring of lung tissue and poor survival. Racial and ethnic minority populations face the greatest risk of morbidity and mortality from disparities impacting respiratory health, but the
Adegunsoye, Ayodeji   +15 more
core   +1 more source

Endothelial cell-derived MMP19 promotes pulmonary fibrosis by inducing E(nd)MT and monocyte infiltration

open access: yesCell Communication and Signaling, 2023
Background Matrix metalloproteinases (MMPs) play important roles in remodeling the extracellular matrix and in the pathogenesis of idiopathic pulmonary fibrosis (IPF).
Weiming Zhao   +11 more
doaj   +1 more source

Breakthrough Solution for Antimicrobial Resistance Detection: Surface‐Enhanced Raman Spectroscopy‐based on Artificial Intelligence

open access: yesAdvanced Materials Interfaces, EarlyView., 2023
This review discusses the use of Surface‐Enhanced Raman Spectroscopy (SERS) combined with Artificial Intelligence (AI) for detecting antimicrobial resistance (AMR). Various SERS studies used with AI techniques, including machine learning and deep learning, are analyzed for their advantages and limitations.
Zakarya Al‐Shaebi   +4 more
wiley   +1 more source

Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis

open access: yesScience Advances, 2020
Human lung single-cell atlas reveals the complexity and diversity of aberrant cellular populations in pulmonary fibrosis. We provide a single-cell atlas of idiopathic pulmonary fibrosis (IPF), a fatal interstitial lung disease, by profiling 312,928 cells
T. Adams   +17 more
semanticscholar   +1 more source

Dietary Phytoestrogens Ameliorate Hydrochloric Acid-Induced Chronic Lung Injury and Pulmonary Fibrosis in Mice [PDF]

open access: yes, 2021
We previously reported that female mice exhibit protection against chemically induced pulmonary fibrosis and suggested a potential role of estrogen. Phytoestrogens act, at least in part, via stimulation of estrogen receptors; furthermore, compared to ...
Catravas, John D.   +3 more
core   +2 more sources

Fat storage-inducing transmembrane proteins: beyond mediating lipid droplet formation

open access: yesCellular & Molecular Biology Letters, 2022
Fat storage-inducing transmembrane proteins (FITMs) were initially identified in 2007 as members of a conserved endoplasmic reticulum (ER) resident transmembrane protein gene family, and were found to be involved in lipid droplet (LD) formation. Recently,
Gaiping Wang   +5 more
doaj   +1 more source

Impact of the new definition for pulmonary hypertension in patients with lung disease: an analysis of the United Network for Organ Sharing database [PDF]

open access: yes, 2022
The implications of the recent change in the definition of pulmonary hypertension on epidemiology and outcomes are not known. We sought to determine the percentage of patients with the two most common lung diseases that would be reclassified regarding ...
Barberà i Mir, Joan Albert   +7 more
core   +1 more source

ADRB2 inhibition combined with antioxidant treatment alleviates lung fibrosis by attenuating TGFβ/SMAD signaling in lung fibroblasts

open access: yesCell Death Discovery, 2023
Idiopathic pulmonary fibrosis is a progressive and fatal interstitial lung disease with a poor prognosis and limited therapeutic options, which is characterized by aberrant myofibroblast activation and pathological remodeling of the extracellular matrix,
Ruyan Wan   +10 more
doaj   +1 more source

COVID‐19 and pulmonary fibrosis: A potential role for lung epithelial cells and fibroblasts

open access: yesImmunological Reviews, 2021
The COVID‐19 pandemic rapidly spread around the world following the first reports in Wuhan City, China in late 2019. The disease, caused by the novel SARS‐CoV‐2 virus, is primarily a respiratory condition that can affect numerous other bodily systems ...
A. John   +3 more
semanticscholar   +1 more source

Roles of Macrophage Polarization and Macrophage-Derived miRNAs in Pulmonary Fibrosis

open access: yesFrontiers in Immunology, 2021
This mini-review summarizes the current evidence for the role of macrophage activation and polarization in inflammation and immune response pertinent to interstitial lung disease, specifically pulmonary fibrosis. In the fibrosing lung, the production and
A. Kishore, M. Petrek
semanticscholar   +1 more source

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