Results 61 to 70 of about 1,876,891 (401)

Correction of therapy of concerned cardiovascular disease and chronic obstructive pulmonary disease in a patient with pulmonary tuberculosis

Клинический разбор в общей медицине, 2021
Chronic obstructive pulmonary disease and cardiovascular diseases (arterial hypertension, coronary heart disease, chronic heart failure) are among the comorbid conditions that mutually aggravate each other.
Natalia V. Bagisheva , Anna V. Mordyk, Dmitry I. Trukhan , Inna A. Viktorova, Marina V. Moiseeva , Anna R. Aroyan, Svetlana V. Sitnikova   +6 more
doaj   +1 more source

Anomalous right pulmonary artery from the aorta [PDF]

, 2006
Anomalous origin of the right pulmonary artery is a rare form of congenital heart disease. It usually presents in early infancy with heart failure and rapid development of pulmonary hypertension. There are about 131 cases reported in the literature and
Mokhtar, S.A.I., Rasool, Aida Hanum Ghulam, Wong, Abdul Rahim   +2 more
core  

Left ventricular heart failure and pulmonary hypertension [PDF]

, 2015
In patients with left ventricular heart failure (HF), the development of pulmonary hypertension (PH) and right ventricular (RV) dysfunction are frequent and have important impact on disease progression, morbidity, and mortality, and therefore warrant ...
Anton Vonk-Noordegraaf, J. Simon R. Gibbs, Jean-Luc Vachiéry, Kovacs, Lancellotti, Nagueh, Rolf Wachter, Stephan Rosenkranz, Teresa De Marco   +8 more
core   +2 more sources

Riociguat for pulmonary arterial hypertension associated with congenital heart disease

Heart, 2015
Objective The Pulmonary Arterial hyperTENsion sGC-stimulator Trial-1 (PATENT-1) was a randomised, double-blind, placebo-controlled phase III trial evaluating riociguat in patients with pulmonary arterial hypertension (PAH).
S. Rosenkranz, H. Ghofrani, M. Beghetti, D. Ivy, R. Frey, A. Fritsch, G. Weimann, S. Saleh, C. Apitz   +8 more
semanticscholar   +1 more source

Adult congenital heart disease and the COVID-19 pandemic

Heart, 2020
Adults with congenital heart disease (ACHD) may be at high risk in the case of COVID-19. Due to the heterogeneity of ACHD and secondary complications, risk profiles are, however, not uniform.
R. Radke, T. Frenzel, H. Baumgartner, G. Diller   +3 more
semanticscholar   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Clinical trials with endothelin receptor antagonists: What went wrong and where can we improve? [PDF]

, 2012
In the early 1990s, within three years of cloning of endothelin receptors, orally active endothelin receptor antagonists (ERAs) were tested in humans and the first clinical trial of ERA therapy in humans was published in 1995.
Barton, Matthias, Cleland, John G., Kohan, Donald E., Rubin, Lewis J., Theodorescu, Dan   +4 more
core   +1 more source

Pulmonary Hypertension Due to Left Heart Diseases

Journal of the American College of Cardiology, 2013
Pulmonary hypertension (PH), a common complication of left heart diseases (LHD), negatively impacts symptoms, exercise capacity, and outcome. Although the true prevalence of PH-LHD is unknown, a subset of patients might present significant PH that cannot be explained by a passive increase in left-sided filling pressures. The term "out-of-proportion" PH
Vachiéry, Jean Luc, Adir, Yochai, Barberà, Joan Albert, Champion, Hunter, Coghlan, John Gerard, Cottin, Vincent, De Marco, Teresa, GALIE', NAZZARENO, Ghio, Stefano, Gibbs, J. Simon R, Martinez, Fernando, Semigran, Marc, Simonneau, Gerald, Wells, Athol, Seeger, Werner   +14 more
openaire   +6 more sources

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Risk of Coronary Heart Disease in People with Chronic Obstructive Pulmonary Disease: A Meta-Analysis

International Journal of COPD, 2021
Jia-Jie Wang Medical College, Soochow University, Suzhou, Jiangsu Province, People’s Republic of ChinaCorrespondence: Jia-Jie WangMedical College, Soochow University, No.
Wang JJ
doaj