Results 61 to 70 of about 674,291 (325)

Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension. [PDF]

, 2018
Concentric lung vascular wall thickening due to enhanced proliferation of pulmonary arterial smooth muscle cells is an important pathological cause for the elevated pulmonary vascular resistance reported in patients with pulmonary arterial hypertension ...
Ayon, Ramon J, Balistrieri, Angela, Black, Stephen M, Chen, Jiwang, Desai, Ankit A, Garcia, Joe GN, Gu, Yali, Makino, Ayako, Rischard, Franz, Song, Shanshan, Tang, Haiyang, Vanderpool, Rebecca, Vinjamuri, Sujana, Wang, Jian, Wang, Ziyi, Wu, Kang, Yuan, Jason X-J, Zhang, Qian, Zhou, Guofei   +18 more
core   +1 more source

Sildenafil for the Treatment of Pulmonary Hypertension in Pediatric Patients [PDF]

, 2009
Sildenafil is a phosphodiesterase 5 inhibitor widely used for the treatment of pulmonary hypertension in children. Despite limited available safety and efficacy evidence, use of sildenafil continues to increase.
Ebenroth, Eric S., Huddleston, Alice J., Knoderer, Chad A., Morris, Jennifer L.   +3 more
core   +2 more sources

Avoidable Hospitalizations in Persons With Rheumatoid Arthritis: A Population‐Based Study Using Administrative Data

Arthritis Care &Research, EarlyView.
Objective We estimated incidence rates of avoidable hospitalizations by persons with rheumatoid arthritis (RA) relative to the general population. Methods We identified individuals meeting a validated case definition for RA based on International Classification of Diseases, Ninth Revision, Clinical Modification (ICD‐9‐CM) and ICD‐10‐CA codes in years ...
Dani G. Contreras, Claire E. H. Barber, J. Antonio Aviña‐Zubieta, Hude Quan, Seungwon Lee, James A. King, Cheryl Barnabe   +6 more
wiley   +1 more source

Right Ventricular Remodeling and Dysfunction in Obstructive Sleep Apnea: A Systematic Review of the Literature and Meta-Analysis

Canadian Respiratory Journal, 2017
Background. Recent studies have reported that obstructive sleep apnea (OSA) patients present alterations in right ventricular (RV) structure and function. However, large randomized controlled trials evaluating the impact of OSA on the right ventricle are
Abdirashit Maripov, Argen Mamazhakypov, Meerim Sartmyrzaeva, Almaz Akunov, Kubatbek Muratali uulu, Melis Duishobaev, Meerim Cholponbaeva, Akylbek Sydykov, Akpay Sarybaev   +8 more
doaj   +1 more source

Nitric oxide activates AMPK by modulating PDE3A in human pulmonary artery smooth muscle cells

Physiological Reports, 2020
Phosphodiesterase 3 (PDE3), of which there are two isoforms, PDE3A and PDE3B, hydrolyzes cAMP and cGMP—cyclic nucleotides important in the regulation of pulmonary vascular tone.
Julie Dillard, Xiaomei Meng, Leif Nelin, Yusen Liu, Bernadette Chen   +4 more
doaj   +1 more source

Case report: The impact of percutaneous atrial septal defect closure in pulmonary hypertension with co-existing cor triatriatum sinister and multiple cardiac comorbidities

Frontiers in Cardiovascular Medicine, 2022
Cor triatriatum sinister is a rare congenital anomaly characterized by the left-sided triatrial form of the heart. Diverse theories have been proposed regarding its formation, and the failure of incorporation of the common pulmonary vein into the left ...
I-Hsin Tai, I-Hsin Tai, I-Hsin Tai, Tsung-Cheng Shyu, Tsung-Cheng Shyu, Tsung-Cheng Shyu, Kai-Sheng Hsieh, Kai-Sheng Hsieh, Kai-Sheng Hsieh, Ke-Wei Chen, Ke-Wei Chen, Wan-Jane Tsai, Kuo-Yang Wang, Kuo-Yang Wang, Kuo-Yang Wang   +14 more
doaj   +1 more source

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

Advanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im, Han‐Gil Jeong, Donghee Kim, Jimin Song, Ngoc Man Phan, Eun‐seo Choi, Young‐Min Kim, Seo‐Hyeon Jeong, Jooho Park, Inwon Park, Jaeyun Kim   +10 more
wiley   +1 more source

Pulmonary arterial hypertension: the burden of disease and impact on quality of life. [PDF]

, 2015
Pulmonary arterial hypertension (PAH) is a debilitating disease that pervades all aspects of a patients daily life. It is also increasingly acknowledged that the burden of PAH extends to older patients and carers.
Delcroix, M, Howard, L
core   +6 more sources

Noninvasive diagnostic modalities and prediction models for detecting pulmonary hypertension associated with interstitial lung disease: a narrative review

European Respiratory Review
Pulmonary hypertension (PH) is highly prevalent in patients with interstitial lung disease (ILD) and is associated with increased morbidity and mortality.
Alexandra Arvanitaki, Gerhard Paul Diller, Michael A. Gatzoulis, Colm McCabe, Laura C. Price, S. John Wort   +5 more
doaj   +1 more source

Pulmonary hypertension

Swiss Medical Weekly, 2003
Pulmonary arterial hypertension (PAH) must be classified into primary pulmonary hypertension and PAH related to other diseases such as collagen vascular diseases, HIV infection or portal hypertension. PAH must also be differentiated from other entities, in particular pulmonary hypertension secondary to thromboembolic diseases, requiring specific ...
openaire   +3 more sources