Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer+10 more
wiley +1 more source
Bronchial Circulation Angiogenesis in the Rat Quantified with SPECT and Micro-CT [PDF]
Introduction As pulmonary artery obstruction results in proliferation of the bronchial circulation in a variety of species, we investigated this angiogenic response using single photon emission computed tomography (SPECT) and micro-CT.
Clough, Anne V.+5 more
core +2 more sources
Chronic Thromboembolic Pulmonary Hypertension Due to Popliteal Vein Aneurysm
Masakazu Tsubono,1,2 Kazuhiro Shimizu,2 Shuji Sato,2 Takuro Ito,2 Takanori Ikeda1 1Department of Internal Medicine, Toho University Omori Medical Center, Tokyo, Japan; 2Department of Internal Medicine, Toho University Sakura Medical Center, Chiba ...
Tsubono M+4 more
doaj
A transistor‐type carbon nanotube gas sensor with dual‐mode detection capability has been proposed. By simply adjusting the gate voltage and UV illumination, this sensor enables both real‐time detection and accumulation‐based sensing of toxic gases within a single device, providing a compact and adaptable platform for environmental monitoring ...
Jaewon Shin+7 more
wiley +1 more source
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness [PDF]
BACKGROUND: There are conflicting data on the effects of antipsychotic medications on delirium in patients in the intensive care unit (ICU). METHODS: In a randomized, double-blind, placebo-controlled trial, we assigned patients with acute ...
Bernard, G.R.+31 more
core +1 more source
Inhibition of LPA-LPAR1 and VEGF-VEGFR2 Signaling in IPF Treatment
Ya-Li Luo,* Yan Li,* Wen Zhou, Si-Yu Wang, Yong-Qi Liu Gansu University Key Laboratory for Molecular Medicine and Chinese Medicine Prevention and Treatment of Major Diseases, Gansu University of Chinese Medicine, Lanzhou, 730000, People’s ...
Luo YL, Li Y, Zhou W, Wang SY, Liu YQ
doaj
Editorial: Reviews in pulmonary medicine 2022. [PDF]
Wang S, Baldi BG.
europepmc +1 more source
THE ESTABLISHMENT OF SANITARIA FOR PULMONARY DISEASES IN THE VICINITY OF OUR GREAT CITIES.Read before the Section for Clinical Medicine. Pathology and Hygiene. of the Massachusetts Medical Society, Suffolk District Medical Society, December 16, 1891. [PDF]
Vincent Y. Bowditch
openalex +1 more source
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao+8 more
wiley +1 more source
Variability in the reported management of pulmonary metastases in osteosarcoma. [PDF]
Nearly 20% of patients with newly diagnosed osteosarcoma have detectable metastases at diagnosis; the majority of which occur in the lungs. There are no established recommendations for the timing and modality of metastasectomy.
Bhattasali, Onita+6 more
core