Results 241 to 250 of about 50,195 (270)

Pulmonary surfactant-associated protein A as a marker of respiratory distress in forensic pathology: assessment of the immunohistochemical and biochemical findings

Legal Medicine, 2003
The aim of the present study was to review the immunohistochemical and biochemical findings with reference to the causes of death in routine casework (total, n=492). In the immunohistochemistry (n=283), an increase in intra-alveolar granular SP-A (SP-A score) was often observed in asphyxiation (n=21/34, 61.8%) and freshwater drowning (n=15/24, 62.5 ...
Hitoshi, Maeda, Masaki Q, Fujita, Bao-Li, Zhu, Kaori, Ishida, Li, Quan, Shigeki, Oritani, Mari, Taniguchi   +6 more
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Postmortem serum levels of pulmonary surfactant-associated proteins A and D with regard to the cause of death in medicolegal autopsy

Legal Medicine, 2009
Pulmonary surfactant-associated proteins A and D (SP-A and -D) are tissue-specific components. Previous studies showed an increase in the postmortem serum SP-A level due to acute pulmonary alveolar damage and acute respiratory distress. The present study comparatively investigated serum SP-A and SP-D levels with regard to the cause of death in serial ...
Li, Quan, Bao-Li, Zhu, Takaki, Ishikawa, Tomomi, Michiue, Dong, Zhao, Chiemi, Yoshida, Jian-Hua, Chen, Qi, Wang, Ayumi, Komatsu, Yoko, Azuma, Hitoshi, Maeda   +10 more
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[The change of pulmonary surfactant associated protein A in acute pulmonary embolism].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2010
To study the changes of pulmonary surfactant associated protein A (SPA) of lung tissue in acute pulmonary embolism (PE).Male SD rats were injected with medical gelfoam microspheres via jugular vein to induce the PE model. Thirty-two rats were randomized into four groups: a control group (n = 8) and three groups of embolism for 24 h (n = 8), 1 week (n =
Chun-ping, Liu, Yun-jian, Zhang, Wei-xuan, Lu, Ying-qun, Ji, Wei-hua, Zhang, Chen, Wang   +5 more
openaire   +1 more source

[The low molecular weight heparin on rat pulmonary surfactant associated protein A of acute pulmonary embolism].

Zhonghua yi xue za zhi, 2008
To explore the effect of low molecular weight heparin (LMWH) on the changes of pulmonary surfactant associated protein A (SPA) of rats in acute pulmonary embolism.Male SD rats were injected with medical gelfoam microspheres via jugular vein to induce PE model. Rats were randomized into three groups: control group (n = 8), embolism for 2 weeks group (n =
Chun-Ping, Liu, Wei-Xuan, Lu, Wei-Guo, Liu, Hang-Wei, Chen, Chen, Wang   +4 more
openaire   +1 more source

[Preparation and identification of monoclonal antibodies against human pulmonary surfactant-associated protein A].

Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2004
To prepare monoclonal antibody (mAb) against human pulmonary surfactant-associated protein A (SP-A) and evaluate its specificities.The hybridoma cell line secreting SP-A mAb was established to induce the production of SP-A ascites fluid in BALB/c mice immunized with SP-A.
Yong-mei, Liu, Zhi-chun, Feng, Jiang, Du, Bing-yi, Wu, Yue-er, Tan, Xian-yan, Wang   +5 more
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[Influence of vasoactive intestinal peptide on expression of pulmonary surfactant associated protein A in lung explants].

Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2012
To study the influence of VIP on the expression of SP-A and its intracellular signal transduction pathway.The influence of VIP on the expression of SP-A was studied by immunohistochemistry and RT-PCR. The intracellular signal transduction pathway was further investigated by using receptor antagonist, protein kinase inhibitor and antisense ...
Lian, Li, Zi-qiang, Luo, Gan-qiou, Wu, Xiu-hong, Sun   +3 more
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Proteomic analysis of human bronchoalveolar lavage fluid: expression profiling of surfactant‐associated protein A isomers derived from human pulmonary alveolar proteinosis using immunoaffinity detection

PROTEOMICS, 2003
AbstractHuman bronchoalveolar lavage fluid (BALF) proteins from pulmonary alveolar proteinosis (PAP) obtained by washing the epithelial lining of the lung with phosphate‐buffered saline, were separated using high resolution two‐dimensional gel electrophoresis (2‐DE) under denaturing and reducing conditions.
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[Influence of ambroxol on paraquat-induced lung tissue injury and change of pulmonary surfactant-associated protein A in the experimental rats].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2007
To investigate the influence of ambroxol on paraquat poisoning induced acute lung tissue injury and the change of pulmonary surfactant associated protein A in the experimental rats.One hundred and twenty healthy adult male Sprague-Dawley rats were randomizedly assigned into normal saline (NS) group (n = 24), paraquat poisoning induced lung tissue ...
Yu-teng, Ma, Ying-ping, Tian, Jian-ling, Su, Han-wen, Shi, Cui-huan, Lv, Zhi-ping, Sun, Jian-hui, Liu, Li, Feng   +7 more
openaire   +1 more source

The coding sequence for the 32,000-dalton pulmonary surfactant-associated protein A is located on chromosome 10 and identifies two separate restriction-fragment-length polymorphisms.

American journal of human genetics, 1987
The primary protein component of human pulmonary surfactant is a 32,000-dalton glycoprotein called surfactant-associated protein A. This protein is important for normal lung function, and its expression is developmentally regulated. Using a mapping panel of somatic-cell hybrids, we have localized the coding sequence for pulmonary surfactant-associated ...
J H, Fisher, F T, Kao, C, Jones, R T, White, B J, Benson, R J, Mason   +5 more
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Isolation and purification of pulmonary surfactant-associated protein A from human amniotic fluid and its bioactivity assessment.

Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA
OBJECTIVE: To isolate and purify pulmonary surfactant-associated protein A(SP-A) from human amniotic fluid. METHODS: Human amniotic fluid was collected from 11 parturients and SP-A was isolated by extraction and dialysis followed by purification procedures.
Yong-Mei, Liu, Zhi-Chun, Feng, Bing-Yi, Wu, Jiang, Du   +3 more
openaire   +1 more source