Results 141 to 150 of about 45,869 (242)

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

Mitochondrial Pyruvate Metabolism Controls Alveolar Stem Cell Fate and Inflammatory Balance. [PDF]

Inflammation
He Z, Li X, Miao X, Xu G, Wang S, Li L, Wu Q, Chen H.   +7 more
europepmc   +1 more source

Structure‐driven immature cotton nanocomposite fibers for ESKAPE pathogen control

Agricultural &Environmental Letters, Volume 11, Issue 1, June 2026.
Abstract Transforming underutilized, low‐quality immature cotton fibers into functional materials provides a sustainable strategy for enhancing economic value. In this study, the intrinsic structural features of immature cotton (Gossypium hirsutum L.) fibers—typically considered as defects in textile processing—were exploited for the in situ synthesis ...
Sunghyun Nam, Md Nayeem Hasan Kashem, Zhongqi He, Noureddine Abidi   +3 more
wiley   +1 more source

Intra- and extrapulmonary lipopolysaccharides-induced acute lung injury and pharmacotherapeutic response patterns in ventilated 7-day-old rabbits. [PDF]

Exp Biol Med (Maywood)
Zhuang G, Gu Q, Xie S, Guo X, Sun B.
europepmc   +1 more source

Modulation of Ferroptosis Biomarkers by Thinned Apple Polyphenols Extract in Acute and Chronic Lung Injuries

eFood, Volume 7, Issue 3, June 2026.
Thinned apple polyphenols (TAP) extract reduced ferroptosis in acute and chronic lung injuries. TAP activated Nrf2 and modulated key biomarkers (MDA, NOX4, GPX4, FTH1), leading to decreased inflammation and fibrosis. These findings suggest TAP as a potential therapeutic approach for lung injury through ferroptosis regulation. ABSTRACT Acute and chronic
Rosalba Siracusa, Alessia Arangia, Marika Cordaro, Roberta Fusco, Salvatore Cuzzocrea, Giancarlo Aldini, Daniela Impellizzeri, Rosanna Di Paola, Ramona D'Amico   +8 more
wiley   +1 more source

Autoimmune Pulmonary Alveolar Proteinosis Triggered by Salazosulfapyridine in a Patient With Rheumatoid Arthritis: A Case Report. [PDF]

Cureus
Ikeuchi T, Yamamoto M, Touge H, Burioka N, Yamasaki A.   +4 more
europepmc   +1 more source

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, Volume 46, Issue 6, Page 1987-2002, June 2026.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source

From Protein Folding to Precision Therapy: Surfactant Protein A in the Spotlight. [PDF]

Am J Respir Cell Mol Biol
Ziehr DR, Chivukula RR.
europepmc   +1 more source

Transcriptomic analysis reveals lipid metabolism and macrophage involvement associated with nintedanib treatment in a rat bleomycin model

British Journal of Pharmacology, Volume 183, Issue 12, Page 3395-3408, June 2026.
In this study, nintedanib reduced lung fibrosis in a rat double‐hit bleomycin‐induced model. Transcriptomic analysis revealed two key gene signatures related to the effect of the molecule: one involving mesenchymal cells affecting known fibrotic pathways and another linking mainly macrophages to lipid metabolism.
Martina Bonatti, Vanessa Pitozzi, Paola Caruso, Silvia Pontis, Maria Gloria Pittelli, Caterina Frati, Denise Madeddu, Federico Quaini, Costanza Anna Maria Lagrasta, Ilaria Minato, Emanuela Bocchi, Maurizio Civelli, Gino Villetti, Marcello Trevisani, Barbara Montanini   +14 more
wiley   +1 more source

Biallelic LAMP3 variants in 5 families with interstitial lung disease: Evidence of a disease-gene association. [PDF]

Genet Med
Keehan LA, Ono-Minagi H, Hadhud M, Rips J, Hinds DM, Fischer AJ, Bartlett JA, McCray PB, Qawasmi N, Nathan N, Louvrier C, Desroziers T, Damme M, Griese M, Wegner DJ, Cole FS, Wambach JA, Wheeler MT, Burbelo PD, Bonner DE, Undiagnosed Diseases Network, Bernstein JA, Chiorini JA, Breuer O, Milla C.   +24 more
europepmc   +1 more source